Intermediates

2-Bromobenzotrifluoride

  • CAS No.392-83-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromobenzotrifluoride (CAS 392-83-6) is a vital organic intermediate for pharmaceuticals and agrochemicals. Available in bulk with certified quality.

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Product Technical Details

Product Overview

2-Bromobenzotrifluoride is a premier organic building block extensively utilized in modern chemical synthesis. Characterized by its unique structural combination of a bromine atom and a trifluoromethyl group on a benzene ring, this compound serves as a critical precursor in the development of complex molecular architectures. Our facility produces this chemical under strict quality control standards to ensure consistency for downstream applications in medicinal chemistry and agrochemical formulation.

As a leading global manufacturer, we understand the importance of reliability in the supply chain. This product is engineered to meet the rigorous demands of industrial-scale reactions, providing excellent reactivity for cross-coupling and nucleophilic substitution processes. The presence of the trifluoromethyl group often enhances the metabolic stability and lipophilicity of final drug candidates, making this intermediate highly valuable in pharmaceutical research.

Technical Specifications

The following table outlines the key physical and chemical properties verified through our internal quality assurance laboratory. Each batch is tested to confirm compliance with international standards.

ParameterSpecification
CAS Number392-83-6
Molecular FormulaC7H4BrF3
Molecular Weight225.01 g/mol
AppearanceWater white or light yellow liquid
Purity≥98.0% (GC)
Density1.652 g/mL at 25 °C
Boiling Point167-168 °C
Refractive Index1.482

Industrial Applications

This fluorinated intermediate finds extensive utility across multiple high-value sectors. In the pharmaceutical industry, it is employed as a key starting material for synthesizing active pharmaceutical ingredients (APIs) where fluorine substitution is required to improve bioavailability. In agrochemicals, it serves as a foundational component for novel pesticide structures that demand high environmental stability.

  • Pharmaceutical Intermediate: Used in the synthesis of neurological and cardiovascular therapeutics.
  • Agrochemical Synthesis: Essential for developing advanced herbicides and fungicides.
  • Dye Manufacturing: Utilized in the production of specialized organic pigments.
  • Organic Synthesis: Acts as a versatile reagent for introducing trifluoromethyl groups.

Quality Assurance and Packaging

We prioritize product integrity from production to delivery. Every drum is sealed to prevent moisture ingress and contamination. Our quality control team performs comprehensive analysis on each lot, ensuring that parameters such as assay purity and physical constants align with the certificate of analysis (COA). Custom packaging solutions are available upon request to accommodate specific logistical requirements.

Storage and Handling

To maintain optimal quality, 2-Bromobenzotrifluoride should be stored in a tightly closed container within a cool, dry, and well-ventilated area. Avoid exposure to direct sunlight and sources of ignition. Proper personal protective equipment (PPE) is recommended during handling to ensure safety in accordance with standard chemical handling protocols. For detailed safety data, please refer to the provided SDS documentation.