Intermediates

2-Bromonicotinic acid

  • CAS No.35905-85-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

2-Bromonicotinic Acid is a high-purity pyridine derivative essential for advanced pharmaceutical and agrochemical synthesis. We offer bulk quantities with strict quality control.

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Product Technical Details

Product Overview

2-Bromonicotinic acid, also known systematically as 2-bromopyridine-3-carboxylic acid, represents a critical building block in modern organic synthesis. This heterocyclic compound features a pyridine ring substituted with a bromine atom at the second position and a carboxylic acid group at the third position. Its unique structural configuration makes it an invaluable precursor for the development of complex pharmaceutical agents and agrochemical formulations. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial applications.

As a specialized chemical intermediate, this compound facilitates various cross-coupling reactions, including Suzuki and Heck couplings, enabling chemists to construct diverse molecular architectures. The presence of the bromine atom provides a reactive site for nucleophilic substitution, while the carboxylic acid group allows for further functionalization through esterification or amidation. This dual reactivity profile underscores its versatility in multi-step synthesis routes.

Key Specifications

ParameterSpecification
CAS Number35905-85-2
Molecular FormulaC6H4BrNO2
Molecular Weight202.005 g/mol
AppearanceOff-white powder
Assay≥99.0%
Melting Point199-203°C
Moisture Content≤0.5%
Heavy Metals≤5ppm

Industrial Applications

The primary utility of 2-Bromonicotinic acid lies in its role as a key intermediate for pharmaceutical manufacturing. It is frequently employed in the synthesis of kinase inhibitors, antiviral agents, and other therapeutic compounds targeting neurological pathways. Additionally, the agrochemical sector utilizes this substance to develop novel pesticides and herbicides with improved environmental profiles. Its stability under standard storage conditions makes it ideal for large-scale production environments.

Researchers value this material for its reliability in catalytic processes. When used in palladium-catalyzed reactions, it delivers high yields with minimal byproduct formation. This efficiency reduces waste and lowers overall production costs for downstream manufacturers. Our quality assurance team rigorously tests each batch to ensure compliance with international standards for organic intermediates.

Quality and Packaging

We maintain strict quality control protocols throughout the production lifecycle. Each shipment is accompanied by a Certificate of Analysis (COA) detailing physical and chemical properties. The product is packaged in 25 kg drums to ensure safety during transit, though custom packaging solutions are available upon request. Proper storage in a cool, ventilated area preserves the integrity of the material over extended periods. Our global logistics network ensures timely delivery to laboratories and production facilities worldwide.