Intermediates

2-Bromopyridine-5-carbaldehyde

  • CAS No.149806-06-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Bromopyridine-5-carbaldehyde (CAS 149806-06-4) designed for pharmaceutical synthesis. Reliable supply for oncology intermediate production with strict quality control.

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Product Technical Details

Product Overview

2-Bromopyridine-5-carbaldehyde is a highly specialized heterocyclic building block extensively utilized in modern medicinal chemistry and organic synthesis. As a brominated pyridine derivative, this compound serves as a critical precursor in the construction of complex molecular architectures, particularly within the pharmaceutical sector. Our manufacturing process ensures exceptional consistency and reliability, making it an ideal choice for research and development teams focused on creating advanced therapeutic agents.

The chemical structure combines the reactivity of an aldehyde group with the versatility of a bromine substituent on the pyridine ring. This unique configuration facilitates various cross-coupling reactions, including Suzuki, Heck, and Sonogashira couplings, which are fundamental steps in synthesizing kinase inhibitors and other targeted therapies. We prioritize the production of this intermediate to meet the rigorous demands of global pharmaceutical supply chains.

Technical Specifications

Quality is the cornerstone of our production philosophy. Each batch of 2-Bromopyridine-5-carbaldehyde undergoes stringent analytical testing to verify compliance with international standards. The following table outlines the key physical and chemical properties guaranteed for our commercial grade material:

ParameterSpecification
Chemical Name2-Bromopyridine-5-carbaldehyde
CAS Number149806-06-4
Molecular FormulaC6H4BrNO
Molecular Weight186.01 g/mol
AppearanceWhite to off-white powder
Purity>99.0% (HPLC)
Melting Point104-110 °C
Boiling Point284.1 °C at 760 mmHg
Density1.683 g/cm3

Industrial Applications

This compound is primarily employed as a key intermediate in the synthesis of sophisticated pharmaceutical APIs. It plays a vital role in the development of oncology therapeutics, including specific kinase inhibitors used in cancer treatment protocols. The high purity level ensures that downstream reactions proceed with minimal byproduct formation, optimizing yield and reducing purification costs for our clients.

Beyond pharmaceuticals, this brominated aldehyde is valuable in agrochemical research and material science where pyridine derivatives are required. Our technical team supports customers with synthesis route optimization, ensuring that the material integrates seamlessly into your existing manufacturing processes. We understand the importance of supply chain stability and offer scalable production capacities to meet both pilot-scale and commercial-volume requirements.

Quality Assurance And Safety

We implement a comprehensive quality management system that covers every stage from raw material sourcing to final packaging. Certificate of Analysis (COA) documents are provided with every shipment, detailing test results for identity, assay, and impurities. Our facility adheres to strict safety protocols to handle reactive chemical intermediates safely.

For storage, the product should be kept in a sealed container within a cool, dry, and well-ventilated warehouse. It is sensitive to air and moisture, so protection under common inert gas is recommended to maintain stability over time. Packaging is typically provided in 20 kg drums, though custom solutions are available to suit specific logistical needs. Contact our sales team for bulk pricing and detailed technical documentation.