2-Chloro-1-fluoro-4-isothiocyanatobenzene
- CAS No.137724-66-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2-chloro-1-fluoro-4-isothiocyanatobenzene for advanced organic synthesis. Reliable bulk supply with full quality documentation.
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Product Overview
2-Chloro-1-fluoro-4-isothiocyanatobenzene is a specialized fluorinated aromatic compound designed for complex organic synthesis applications. This reactive intermediate features a stable isothiocyanate group attached to a chloro-fluorobenzene ring, making it an essential building block for pharmaceutical and agrochemical research. Our manufacturing process ensures exceptional purity and consistency, meeting the rigorous demands of modern chemical development.
The unique combination of chlorine and fluorine substituents enhances the compound's reactivity and metabolic stability in downstream derivatives. It serves as a critical precursor in the construction of heterocyclic systems and biologically active molecules. We prioritize quality control at every stage, from raw material selection to final packaging, to guarantee performance in your synthesis workflows.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 137724-66-4 |
| Molecular Formula | C7H3ClFNS |
| Molecular Weight | 187.62 g/mol |
| Appearance | Colorless to pale yellow transparent liquid |
| Assay | ≥99.0% |
| Density | 1.31 g/cm3 |
| Boiling Point | 115-117 °C (11 mmHg) |
| Flash Point | 130-132 °C |
Key Features
- High chemical purity suitable for sensitive synthesis routes
- Stable fluorinated structure for enhanced derivative performance
- Reactive isothiocyanate group for efficient coupling reactions
- Consistent quality backed by comprehensive Certificate of Analysis
- Available in bulk quantities to support industrial scale production
Industrial Applications
This compound is primarily utilized as a versatile intermediate in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals. The isothiocyanate functionality allows for straightforward conversion into thioureas, thioamides, and other sulfur-containing heterocycles. Researchers value this building block for its ability to introduce specific halogen patterns that influence biological activity and physicochemical properties.
Common applications include the development of kinase inhibitors, receptor modulators, and crop protection agents. The presence of both chloro and fluoro substituents provides opportunities for selective functionalization, enabling chemists to construct complex molecular architectures with precision. Our global supply chain ensures timely delivery for research and development projects worldwide.
Storage and Safety
To maintain optimal stability, store this product in a cool, ventilated area away from direct sunlight and moisture. Keep containers tightly sealed when not in use to prevent hydrolysis of the isothiocyanate group. Standard laboratory safety protocols should be followed during handling, including the use of appropriate personal protective equipment. We provide detailed safety data sheets with every shipment to ensure compliance with local regulations and safe operational practices.
