2-Chloro-1-methylpyridinium Iodide
- CAS No.14338-32-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity condensation reagent for peptide synthesis and organic coupling reactions. Available in bulk with full quality documentation.
Request Bulk PricingProduct Technical Details
Product Overview
2-Chloro-1-methylpyridinium Iodide, commonly recognized in the industry as CMPI or the Mukaiyama Reagent, stands as a pivotal chemical agent in modern organic synthesis. This specialized pyridinium salt is extensively utilized for its exceptional ability to activate carboxylic acids, facilitating efficient condensation reactions. Our manufacturing process ensures that every batch meets rigorous international standards, providing chemists and production facilities with a reliable tool for complex molecular construction.
As a leading global manufacturer, we understand the critical nature of reagent purity in downstream synthesis. Therefore, our 2-Chloro-1-methylpyridinium Iodide is produced under strict quality control protocols to guarantee consistency and performance in sensitive chemical environments.
Technical Specifications
The following table outlines the key physical and chemical parameters verified during our quality assurance process. Each shipment is accompanied by a Certificate of Analysis (COA) to validate these metrics.
| Parameter | Specification |
|---|---|
| CAS Number | 14338-32-0 |
| Molecular Formula | C6H7ClIN |
| Molecular Weight | 255.48 g/mol |
| Appearance | Yellow crystalline powder |
| Purity (HPLC) | ≥99.0% |
| Melting Point | 195-200°C |
| Refractive Index | 1.546 |
Industrial Applications
This condensation reagent is primarily employed in the pharmaceutical and fine chemical sectors. Its primary function involves the activation of carboxyl groups to form esters and amides, making it indispensable in peptide synthesis workflows. Unlike traditional coupling methods, CMPI offers milder reaction conditions and reduced racemization risks, preserving the stereochemical integrity of chiral molecules.
Beyond peptide coupling, it serves as a versatile intermediate in the synthesis of macrolides and other complex organic structures. Researchers value its solubility profile and reactivity, which allow for streamlined processes in both laboratory-scale discovery and pilot-scale manufacturing.
Quality Advantages
- High Chemical Purity: Ensures minimal side reactions and higher yields in final products.
- Consistent Batch Quality: Advanced manufacturing processes guarantee lot-to-lot reproducibility.
- Technical Support: Our team provides detailed usage guidelines and safety data.
- Global Compliance: Produced in facilities adhering to strict environmental and safety regulations.
Packaging and Storage
To maintain stability and potency, 2-Chloro-1-methylpyridinium Iodide is packaged in secure 25 kg drums. Custom packaging solutions are available to meet specific logistical requirements. The product should be stored in a cool, ventilated area away from direct sunlight and moisture. Proper handling procedures must be followed to ensure safety during transport and usage. We offer global shipping options with comprehensive documentation to facilitate smooth customs clearance.
