Intermediates

2-Chloro-3,5-dinitrobenzotrifluoride

  • CAS No.392-95-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2-Chloro-3,5-dinitrobenzotrifluoride (CAS 392-95-0) designed for advanced organic synthesis and fluorinated compound manufacturing.

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Product Technical Details

Product Overview

2-Chloro-3,5-dinitrobenzotrifluoride is a sophisticated fluorinated aromatic intermediate that plays a critical role in modern organic synthesis. Characterized by the presence of a trifluoromethyl group alongside chloro and nitro substituents, this compound offers unique reactivity profiles essential for constructing complex molecular architectures. Our manufacturing process ensures exceptional batch-to-batch consistency, making it a reliable choice for research and industrial scale applications.

The integration of fluorine atoms into organic molecules is a strategic approach in medicinal chemistry and agrochemical development. This specific derivative provides a robust platform for nucleophilic aromatic substitution reactions. The electron-withdrawing nature of the nitro groups activates the aromatic ring, facilitating selective transformations that are vital for producing high-value downstream products.

Technical Specifications

We adhere to strict quality control protocols to guarantee the integrity of every shipment. The physical and chemical properties are rigorously tested to meet international standards for fine chemical intermediates.

ParameterSpecification
CAS Number392-95-0
Molecular FormulaC7H2ClF3N2O4
Molecular Weight270.550 g/mol
AppearanceLight yellow crystal
Purity (Assay)≥96.0%
Melting Point62-64 °C
Boiling Point285.0±35.0 °C
Density1.7±0.1 g/cm3
Flash Point126.2±25.9 °C

Industrial Applications

This compound serves as a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. The trifluoromethyl moiety is particularly valued for enhancing metabolic stability and lipophilicity in drug candidates. Chemists utilize this intermediate to introduce fluorine content into lead compounds, optimizing their pharmacokinetic properties.

In the agrochemical sector, it acts as a precursor for herbicides and pesticides where environmental stability is required. The reactivity of the chloro and nitro groups allows for diverse functionalization, including reduction to amines or displacement by nucleophiles. This flexibility supports the development of novel active ingredients with improved efficacy profiles.

Storage and Handling

To maintain optimal quality, store this material in a cool, ventilated area away from direct sunlight and moisture. Proper handling procedures should be followed in accordance with safety data sheets. We recommend using appropriate personal protective equipment during manipulation to ensure workplace safety. Packaging is available in 25 kg drums, with custom options available to suit specific logistical requirements.

Quality Assurance

As a global manufacturer, we provide comprehensive documentation including Certificates of Analysis (COA) for every batch. Our commitment to industrial purity ensures that your synthesis routes proceed without interruption due to impurity-related side reactions. Contact our technical team for detailed specifications or to discuss custom synthesis needs tailored to your project goals.