2-Chloro-3-fluoro-4-methylpyridine
- CAS No.881891-82-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2-Chloro-3-fluoro-4-methylpyridine is a specialized fluorinated pyridine intermediate designed for advanced pharmaceutical synthesis and organic chemistry applications.
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Product Overview
2-Chloro-3-fluoro-4-methylpyridine represents a critical building block in the realm of modern medicinal chemistry and organic synthesis. As a substituted pyridine derivative, this compound features a unique halogenated structure that facilitates diverse chemical transformations. Our manufacturing process ensures consistent quality, making it an ideal choice for researchers and industrial chemists seeking reliable raw materials for complex molecule construction.
The presence of both chloro and fluoro substituents on the pyridine ring enhances the reactivity profile of this intermediate, allowing for selective nucleophilic substitutions and cross-coupling reactions. This versatility is essential for developing novel pharmaceutical agents and agrochemical compounds. We prioritize strict quality control measures to guarantee that every batch meets the rigorous demands of downstream synthesis.
Technical Specifications
Our production facility adheres to international standards to deliver products with high chemical integrity. The following table outlines the key physical and chemical parameters verified during our quality assurance protocols.
| Parameter | Specification |
|---|---|
| CAS Number | 881891-82-3 |
| Molecular Formula | C6H5ClFN |
| Molecular Weight | 145.56 g/mol |
| Appearance | Yellow liquid |
| Purity | ≥98.0% |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 186.4±35.0 °C at 760 mmHg |
| Flash Point | 66.5±25.9 °C |
| Refractive Index | 1.504 |
Industrial Applications
This fluorinated pyridine derivative serves primarily as a pharmaceutical intermediate. It is extensively utilized in the synthesis of active pharmaceutical ingredients (APIs) where specific halogen positioning is required for biological activity. The compound acts as a precursor for various heterocyclic systems, enabling chemists to introduce specific functional groups with high precision.
- Pharmaceutical synthesis for novel drug candidates.
- Organic chemistry research and development.
- Production of agrochemical intermediates.
- Material science applications requiring fluorinated motifs.
By integrating this intermediate into your synthesis route, you can achieve improved yields and selectivity in multi-step reactions. Our global supply chain ensures that bulk quantities are available to support large-scale manufacturing needs without compromising on purity or consistency.
Storage and Handling
Proper storage is essential to maintain the stability and safety of 2-Chloro-3-fluoro-4-methylpyridine. The product should be kept in a tightly closed container to prevent moisture absorption and contamination. It is recommended to store the material in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizing agents.
Given the flash point of approximately 66.5 degrees Celsius, standard flammable liquid handling procedures should be followed. Personnel must wear appropriate personal protective equipment, including chemical-resistant gloves and safety goggles, during handling operations. In case of spills, absorb with inert material and dispose of according to local environmental regulations. We provide a comprehensive Certificate of Analysis (COA) with every shipment to verify compliance with safety and quality standards.
