Intermediates

2-Chloro-3-fluoro-5-methylpyridine

  • CAS No.34552-15-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Chloro-3-fluoro-5-methylpyridine (CAS 34552-15-3) designed for advanced pharmaceutical synthesis. Available in bulk quantities with strict quality control.

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Product Technical Details

Product Overview

2-Chloro-3-fluoro-5-methylpyridine represents a critical fluorinated heterocyclic building block within the modern chemical industry. As a specialized pyridine derivative, this compound features a unique substitution pattern that enhances its reactivity and utility in complex organic synthesis. Our facility produces this intermediate under stringent quality management systems to ensure consistency across every batch supplied to global partners.

The molecular structure incorporates both chloro and fluoro substituents on the pyridine ring, providing versatile handles for further functionalization. This specific arrangement is highly valued in medicinal chemistry and agrochemical development, where precise molecular architecture is required to achieve desired biological activity profiles. We maintain a robust supply chain to support large-scale production needs.

Technical Specifications

Quality assurance is paramount in the production of fine chemical intermediates. Each lot undergoes rigorous analytical testing to confirm identity and purity levels. The physical properties are consistent with theoretical values, ensuring reliable performance in downstream reactions. Below are the key specification parameters for this material.

ParameterSpecification
Chemical Name2-Chloro-3-fluoro-5-methylpyridine
CAS Number34552-15-3
Molecular FormulaC6H5ClFN
Molecular Weight145.56 g/mol
AppearanceWhite Crystalline Powder
Purity≥98.0%
Boiling Point186.4±35.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Refractive Index1.504

Industrial Applications

This fluorinated pyridine derivative serves primarily as a pharmaceutical intermediate. It is utilized in the synthesis of advanced therapeutic agents where the introduction of fluorine atoms can significantly improve metabolic stability and bioavailability. The chloro group offers a site for nucleophilic substitution, allowing chemists to build complex molecular frameworks efficiently.

Beyond pharmaceuticals, this compound finds application in the development of specialty agrochemicals and functional materials. The stability of the carbon-fluorine bond makes it an excellent candidate for creating durable chemical structures. Our team works closely with R&D departments to provide technical support for integration into various synthesis routes.

Quality Assurance and Safety

We adhere to international safety standards for the handling and storage of chemical intermediates. The product should be stored in a tightly closed container within a cool, dry environment to prevent degradation. Proper ventilation is recommended during handling to minimize exposure to vapors. Personal protective equipment, including gloves and safety goggles, must be worn at all times.

Every shipment is accompanied by a Certificate of Analysis (COA) detailing the test results for that specific batch. We offer flexible packaging options, including 25 kg drums, to suit different logistical requirements. Our commitment to quality ensures that clients receive materials that meet their exacting standards for industrial purity and performance.