Intermediates

2-Chloro-3-fluoropyridine

  • CAS No.17282-04-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Chloro-3-fluoropyridine (CAS 17282-04-1) designed for pharmaceutical synthesis. Reliable supply with strict quality control for global research and production needs.

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Product Technical Details

Product Overview

2-Chloro-3-fluoropyridine is a highly valuable halogenated heterocyclic compound that serves as a fundamental building block in modern medicinal chemistry and organic synthesis. Characterized by the presence of both chloro and fluoro substituents on the pyridine ring, this molecule offers unique reactivity profiles that are essential for the construction of complex pharmaceutical architectures. Our manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal choice for research laboratories and large-scale production facilities alike.

The strategic positioning of the halogen atoms allows for selective nucleophilic substitution and transition-metal catalyzed cross-coupling reactions. This versatility makes the compound a preferred precursor in the development of kinase inhibitors, agrochemical agents, and advanced functional materials. As a trusted global manufacturer, we prioritize purity and safety to support your downstream synthesis requirements without compromise.

Key Specifications

We adhere to rigorous quality control standards to guarantee the performance of our chemical intermediates. Each batch undergoes comprehensive testing using advanced analytical techniques such as GC and HPLC to verify composition and purity levels. The following table outlines the typical physical and chemical properties associated with this product:

ParameterSpecification
CAS Number17282-04-1
Molecular FormulaC5H3ClFN
Molecular Weight131.54 g/mol
AppearanceColorless to pale yellow liquid
Purity≥98.0%
Density1.3±0.1 g/cm3
Boiling Point151.6±20.0 °C at 760 mmHg
Flash Point45.5±21.8 °C

Industrial Applications

The primary application of 2-Chloro-3-fluoropyridine lies within the pharmaceutical industry, where it acts as a critical intermediate for active pharmaceutical ingredients (APIs). Its chemical structure facilitates various transformation reactions, enabling chemists to introduce specific functional groups with high precision. Beyond pharmaceuticals, this compound finds utility in the agrochemical sector for the synthesis of novel pesticides and herbicides.

  • Essential building block for heterocyclic drug candidates.
  • Utilized in palladium-catalyzed coupling reactions.
  • Supports the development of neurological and oncology therapeutics.
  • Compatible with diverse synthetic routes and scaling processes.

Quality Assurance and Storage

Quality assurance is the cornerstone of our operation. We provide a Certificate of Analysis (COA) with every shipment, detailing the specific test results for purity, identity, and physical constants. To maintain product integrity, proper storage conditions are essential. The material should be kept in a tightly closed container within a cool, dry, and well-ventilated area. Protection from moisture and direct sunlight is recommended to prevent degradation over time.

Partnering with us ensures access to a stable supply chain, competitive bulk pricing, and technical support from experienced chemical engineers. Whether you require standard quantities for research or metric tons for industrial manufacturing, we are equipped to meet your demands with professionalism and speed. Contact our sales team today to request a quote or discuss your specific synthesis requirements.