Intermediates

2-Chloro-3-iodopyridine

  • CAS No.78607-36-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Chloro-3-iodopyridine (CAS 78607-36-0) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and agrochemical research.

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Product Technical Details

Product Overview

2-Chloro-3-iodopyridine represents a critical heterocyclic building block within the realm of advanced organic synthesis and chemical manufacturing. As a specialized halogenated pyridine derivative, this compound offers unique reactivity profiles that make it indispensable for constructing complex molecular architectures in both academic and industrial settings. Our manufacturing process ensures high consistency and purity, catering to the rigorous demands of research and development laboratories as well as large-scale production facilities requiring reliable raw materials.

The strategic presence of both chloro and iodo substituents on the pyridine ring provides versatile handles for various cross-coupling reactions. This dual functionality allows chemists to selectively functionalize the molecule, enabling the stepwise construction of sophisticated pharmaceutical candidates and agrochemical agents without compromising structural integrity. We prioritize quality control at every stage of production to deliver a reliable material for your synthesis pathways, ensuring that each batch meets stringent international standards for chemical intermediates.

Technical Specifications

Our commitment to quality is reflected in the detailed specifications of this chemical intermediate. Each batch undergoes rigorous analytical testing using advanced chromatography and spectroscopy methods to confirm identity and purity levels. The following table outlines the key physical and chemical parameters guaranteed for our standard grade material, providing transparency for our global partners.

ParameterValue
CAS Number78607-36-0
Molecular FormulaC5H3ClIN
Molecular Weight239.441 g/mol
AppearanceLight Yellow To Yellow Crystal
Assay≥98.0%
Moisture Content≤0.5%
Melting Point93-96 °C
Boiling Point261.2±20.0 °C
Flash Point111.8±21.8 °C
Density2.1±0.1 g/cm3

Industrial Applications

This compound serves primarily as a versatile intermediate in the synthesis of fine chemicals and specialized materials. Its structural features make it particularly suitable for palladium-catalyzed coupling reactions, such as Suzuki, Heck, or Sonogashira couplings, which are fundamental processes in modern medicinal chemistry. Researchers utilize this building block to introduce specific functional groups into heterocyclic systems, which is a common strategy in drug discovery programs and material science innovations.

  • Pharmaceutical Intermediate Synthesis
  • Agrochemical Research And Development
  • Material Science Applications
  • Custom Organic Synthesis Projects
  • Laboratory Reagent For Coupling Reactions

By providing a high-purity starting material, we help reduce impurities in downstream processes, thereby improving overall yield and simplifying purification steps. Our team understands the importance of supply chain stability for continuous production lines and offers consistent quality to support your long-term projects. The reliability of this intermediate is crucial for maintaining reproducibility in experimental results and commercial manufacturing outcomes.

Storage And Handling

To maintain the integrity of 2-Chloro-3-iodopyridine, proper storage conditions are essential for preserving its chemical stability over time. The material should be kept in a cool, ventilated area away from direct sunlight and moisture sources to prevent potential degradation. Containers must be tightly sealed when not in use to prevent contamination from atmospheric elements or other chemical vapors. We recommend following standard safety protocols for handling halogenated organic compounds, including the use of appropriate personal protective equipment such as gloves and safety goggles.

For bulk orders, we offer flexible packaging solutions, typically 25 kg per drum, though custom packaging configurations are available upon request to suit specific logistical needs. Our logistics network ensures timely delivery to global destinations while maintaining compliance with international shipping regulations for chemical goods. Contact our technical support team for detailed safety data sheets and comprehensive guidance on integrating this intermediate into your specific manufacturing processes.