2-Chloro-3-picoline
- CAS No.18368-76-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
2-Chloro-3-Picoline is a high-purity liquid intermediate essential for synthesizing nicotinic acid derivatives. We offer reliable bulk supply with strict quality control.
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Product Overview
2-Chloro-3-picoline stands as a pivotal heterocyclic building block within the modern fine chemical and pharmaceutical industries. As a chlorinated derivative of picoline, this compound offers unique reactivity profiles that make it indispensable for complex organic synthesis pathways. Our facility specializes in the large-scale production of this high-value intermediate, ensuring consistent supply chains for downstream manufacturers who require reliability and precision in their raw materials.
The molecular structure features a chlorine atom at the second position and a methyl group at the third position of the pyridine ring. This specific substitution pattern facilitates various nucleophilic substitution reactions and oxidation processes. Consequently, it serves as a foundational precursor for producing a wide array of agrochemicals, pharmaceuticals, and functional materials. Our commitment to excellence ensures that every batch meets rigorous international standards for purity and performance.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 18368-76-8 |
| Molecular Formula | C6H6ClN |
| Molecular Weight | 127.57 g/mol |
| Appearance | Colourless to yellow transparent liquid |
| Assay (GC) | ≥98.0% |
| Moisture Content | ≤0.5% |
| Density | 1.17 g/cm3 |
| Boiling Point | 192-193°C |
| Refractive Index | 1.533 |
Industrial Applications
The primary utility of 2-Chloro-3-picoline lies in its role as a key intermediate for the synthesis of 2-Chloronicotinic acid and its derivatives. These downstream products are critical components in the manufacturing of novel pharmaceutical agents and crop protection solutions. The chloro group provides an active site for coupling reactions, while the methyl group can be oxidized to form carboxylic acid functionalities, expanding the synthetic versatility of this molecule.
- Pharmaceutical Synthesis: Used in creating kinase inhibitors and other therapeutic agents.
- Agrochemical Production: Essential for developing herbicides and fungicides.
- Material Science: Employed in the creation of specialized polymers and ligands.
- Custom Organic Synthesis: Available for bespoke research and development projects.
Quality Assurance and Packaging
Quality control is paramount in our manufacturing process. Each production lot undergoes comprehensive analysis using gas chromatography and other advanced analytical techniques to verify purity levels and impurity profiles. We provide a Certificate of Analysis (COA) with every shipment, ensuring full transparency and compliance with your internal quality standards. Our logistics team manages packaging securely to prevent degradation during transit.
Standard packaging includes 200 kg drums, though we offer flexible customization to meet specific client requirements. Storage recommendations include keeping the material in a cool, ventilated area away from direct sunlight and incompatible substances. As a global manufacturer, we support clients with competitive bulk pricing and reliable delivery schedules, positioning ourselves as a trusted partner in your supply chain.
