2-Chloro-3-(trifluoromethyl)pyridine
- CAS No.65753-47-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Chloro-3-(trifluoromethyl)pyridine (CAS 65753-47-1) is a key fluorinated intermediate for pharmaceutical synthesis. We offer bulk supply with strict quality control.
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Product Overview
2-Chloro-3-(trifluoromethyl)pyridine represents a critical class of fluorinated heterocyclic compounds utilized extensively in modern medicinal chemistry and organic synthesis. As a specialized building block, this substance features a pyridine ring substituted with both chloro and trifluoromethyl functional groups, providing unique reactivity profiles for complex molecular construction. Our facility produces this intermediate under stringent quality management systems to ensure consistency across large-scale batches.
The incorporation of fluorine atoms into organic molecules is a strategic approach in drug design to enhance metabolic stability and bioavailability. This specific pyridine derivative serves as a versatile precursor for developing novel therapeutic agents. We maintain a robust supply chain to support research laboratories and manufacturing partners globally, ensuring timely delivery and reliable stock availability for your production needs.
Technical Specifications
Our manufacturing process adheres to international standards for fine chemicals. Each batch undergoes rigorous analytical testing to confirm identity and purity levels. The physical properties listed below are representative of our standard commercial grade material, suitable for most synthetic applications requiring high fidelity reagents.
| Parameter | Value |
|---|---|
| CAS Number | 65753-47-1 |
| Molecular Formula | C6H3ClF3N |
| Molecular Weight | 181.54 g/mol |
| Purity | ≥98.0% |
| Appearance | Colorless crystalline powder |
| Melting Point | 36-40 °C |
| Boiling Point | 181.7 °C at 760 mmHg |
| Density | 1.4 g/cm3 |
Industrial Applications
This fluorinated pyridine intermediate is primarily employed in the synthesis of advanced pharmaceutical compounds. It acts as a key scaffold in the preparation of high affinity receptor antagonists, particularly within the field of pain management research. The chemical stability of the trifluoromethyl group allows for diverse downstream transformations without compromising structural integrity.
- Synthesis of TRPV1 receptor antagonists for neurological therapeutics.
- Development of agrochemical active ingredients requiring fluorinated heterocycles.
- Use as a coupling partner in cross-coupling reactions for medicinal chemistry.
- Production of specialized ligands for biochemical assay development.
Quality Assurance And Storage
We prioritize product safety and stability throughout the logistics process. All materials are packaged in secure containers to prevent moisture absorption and contamination. A Certificate of Analysis (COA) is provided with every shipment to verify compliance with specified parameters. Proper storage conditions are essential to maintain the quality of this chemical over time.
Store in a tightly closed container in a cool, dry environment away from incompatible substances such as strong oxidizing agents. Our team is available to provide technical support regarding handling procedures and regulatory documentation. Contact us for detailed safety data sheets and customized packaging options for bulk orders.
