Intermediates

2-Chloro-4,5-Difluorotoluene

  • CAS No.252936-45-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade 2-Chloro-4,5-Difluorotoluene supplied for advanced organic synthesis. Ideal for pharmaceutical and agrochemical intermediate manufacturing with high purity standards.

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Product Technical Details

Product Overview

2-Chloro-4,5-Difluorotoluene is a highly specialized fluorinated aromatic compound designed for use in complex organic synthesis pathways. As a critical building block, this chemical facilitates the introduction of fluorine and chlorine substituents into molecular structures, enhancing the metabolic stability and bioavailability of final active pharmaceutical ingredients. Our manufacturing process ensures consistent quality and reliability for large-scale industrial applications.

This compound serves as a versatile precursor in the development of novel therapeutics and crop protection agents. The specific arrangement of halogen atoms on the toluene ring provides unique reactivity profiles, allowing chemists to perform selective substitutions and coupling reactions with high precision. We prioritize strict quality control measures to guarantee that every batch meets rigorous international standards.

Key Specifications

Our production facility utilizes advanced distillation and purification technologies to achieve superior purity levels. The physical and chemical properties are meticulously verified through comprehensive analytical testing. Below are the standard specifications for our commercial grade material.

ParameterSpecification
CAS Number252936-45-1
Molecular FormulaC7H5ClF2
Molecular Weight162.56 g/mol
AppearanceLight yellow transparent liquid
Purity≥98.0%
Water Content≤0.5%
Density1.3±0.1 g/cm3
Boiling Point161.8±35.0 °C at 760 mmHg
Flash Point54.7±19.4 °C
Refractive Index1.482

Industrial Applications

The primary utility of 2-Chloro-4,5-Difluorotoluene lies in its role as a strategic intermediate for the pharmaceutical and agrochemical sectors. Fluorinated compounds are increasingly demanded in modern drug design due to their ability to improve binding affinity and resistance to enzymatic degradation. This product enables the synthesis of diverse chemical libraries aimed at discovering new medicinal candidates.

In the agrochemical industry, this substance is utilized to create advanced herbicides and fungicides. The presence of fluorine atoms often enhances the environmental stability and efficacy of these agents. Our clients leverage this intermediate to develop next-generation solutions for sustainable agriculture. We support various synthesis routes and can provide technical guidance for optimal integration into your manufacturing process.

Quality Assurance and Safety

We maintain a robust quality management system to ensure product consistency. Each shipment is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. Our logistics team ensures safe packaging using plastic drums or plastic-coated iron drums, typically in 25kg units. Proper storage involves keeping containers tightly closed in a cool, dry, and well-ventilated area away from incompatible materials.

Safety is paramount in handling fluorinated aromatics. Users should adhere to standard laboratory safety protocols, including the use of appropriate personal protective equipment. We are committed to being a reliable global manufacturer, offering competitive bulk pricing and responsive technical support to meet your project requirements efficiently.