2-(Chloro(4-chlorophenyl)methyl)pyridine
- CAS No.142404-69-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-(Chloro(4-chlorophenyl)methyl)pyridine (CAS 142404-69-1), a key pharmaceutical intermediate for Bepotastine besilate synthesis.
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Product Overview
2-(Chloro(4-chlorophenyl)methyl)pyridine is a high-value aromatic heterocyclic compound widely employed as a critical building block in the synthesis of advanced pharmaceutical actives. With a molecular formula of C12H9Cl2N and a molecular weight of 238.11 g/mol, this dichlorinated pyridine derivative exhibits excellent reactivity in nucleophilic substitution and cross-coupling reactions, making it indispensable in modern medicinal chemistry workflows.
Specifications
| Molecular Formula | C12H9Cl2N |
|---|---|
| Molecular Weight | 238.113 g/mol |
| Density | 1.279 g/cm³ |
| Boiling Point | 338.7°C at 760 mmHg |
| Flash Point | 189.1°C |
| Refractive Index | 1.597 |
| Appearance | White powder |
| Purity | ≥99% |
Industrial Applications
This compound serves primarily as a synthetic intermediate in the production of Bepotastine besilate (CAS 190786-44-8), a second-generation antihistamine used in ophthalmic and oral formulations for allergic conditions. Its dual chlorine functionality enables selective derivatization, facilitating efficient construction of complex molecular architectures under controlled reaction conditions.
- Enables streamlined synthesis of histamine H1-receptor antagonists
- Compatible with standard organometallic and palladium-catalyzed coupling protocols
- Supplied in pharma-grade purity to meet stringent regulatory requirements
Stored in a cool, dry, and tightly sealed container away from moisture, heat, and direct light. Standard packaging is 25 kg per fiber drum, with custom options available upon request.
