Intermediates

2-Chloro-4-fluorobenzoic acid

  • CAS No.2252-51-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Chloro-4-fluorobenzoic acid designed for advanced organic synthesis and pharmaceutical intermediate applications.

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Product Technical Details

Product Overview

2-Chloro-4-fluorobenzoic acid represents a critical halogenated aromatic building block within the modern chemical industry. This specialized compound is extensively utilized as a key intermediate in the synthesis of complex pharmaceutical agents, agrochemical formulations, and advanced functional materials. Our manufacturing process ensures exceptional consistency and purity, making it an ideal choice for research and development teams as well as large-scale production facilities requiring reliable raw materials.

The unique substitution pattern of chlorine and fluorine atoms on the benzoic acid backbone provides distinct reactivity profiles that are essential for multi-step organic synthesis. This molecular structure allows for selective functionalization, enabling chemists to construct sophisticated molecular architectures with high precision. As a trusted global manufacturer, we prioritize quality control at every stage of production to meet the rigorous demands of the life sciences sector.

Physical and Chemical Properties

Understanding the physicochemical characteristics of this compound is vital for safe handling and effective integration into synthesis routes. The substance presents as a stable white powder under standard conditions, facilitating easy weighing and transfer in laboratory and plant environments. Its thermal stability and solubility profiles are optimized for various reaction conditions, ensuring compatibility with diverse synthetic protocols.

ParameterSpecification
CAS Number2252-51-9
Molecular FormulaC7H4ClFO2
Molecular Weight174.56 g/mol
AppearanceWhite powder
Assay≥98.0%
Melting Point181-183°C
Density1.477 g/cm3
Moisture Content≤0.2%

Industrial Applications

The primary utility of 2-Chloro-4-fluorobenzoic acid lies in its role as a versatile precursor for pharmaceutical active ingredients. It serves as a foundational component in the development of novel therapeutic compounds, particularly those targeting neurological and cardiovascular conditions. The presence of the fluorine atom often enhances metabolic stability and bioavailability in final drug products, making this intermediate highly valuable in medicinal chemistry.

Beyond pharmaceuticals, this chemical finds application in the agrochemical sector for the synthesis of herbicides and pesticides. Its reactivity allows for the creation of robust molecular structures capable withstanding environmental stressors. Additionally, it is utilized in the production of liquid crystals and polymeric materials where specific electronic properties are required. Our team provides comprehensive technical support to help clients optimize their synthesis routes using this material.

Quality Assurance and Storage

We adhere to strict quality management systems to guarantee that every batch meets or exceeds industry standards. Each shipment is accompanied by a Certificate of Analysis (COA) detailing comprehensive test results. To maintain integrity, the product should be stored in a cool, ventilated area away from direct sunlight and moisture. Proper packaging ensures protection during transit, with standard options including 25 kg drums or customized solutions based on specific client requirements.