Intermediates

(2-Chloro-4-fluorophenyl)methanol

  • CAS No.208186-84-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity (2-Chloro-4-fluorophenyl)methanol is a premium fluorinated intermediate designed for complex organic synthesis and pharmaceutical manufacturing processes.

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Product Technical Details

Product Overview

(2-Chloro-4-fluorophenyl)methanol represents a critical fluorinated building block within the modern chemical industry. This specialized organic compound is engineered to meet the rigorous demands of advanced medicinal chemistry and agrochemical development. As a key intermediate, it facilitates the construction of complex molecular architectures required for next-generation therapeutics. The presence of both chlorine and fluorine substituents on the benzyl alcohol scaffold provides unique electronic and steric properties that enhance metabolic stability and bioavailability in downstream applications.

Our manufacturing process ensures consistent quality and reliability for large-scale production needs. We understand that precision in chemical synthesis starts with the purity of the raw materials. Therefore, every batch undergoes stringent quality control protocols to verify structural integrity and compositional accuracy. This commitment to excellence makes our product a preferred choice for research laboratories and industrial manufacturing facilities worldwide.

Technical Specifications

To support seamless integration into your synthesis workflows, we provide comprehensive physical and chemical data. The following table outlines the standard specifications for this material. Custom specifications may be available upon request to accommodate specific project requirements.

ParameterSpecification
CAS Number208186-84-9
Molecular FormulaC7H6ClFO
Molecular Weight160.57 g/mol
AppearanceOff-white to pale yellow crystalline powder
Assay (Purity)≥98.0%
Moisture Content≤0.2%
Melting Point45-48°C
Boiling Point233.1°C
Density1.344 g/cm3

Industrial Applications

This fluorinated benzyl alcohol derivative serves as a versatile precursor in various organic synthesis routes. It is particularly valuable in the preparation of kinase inhibitors and other targeted therapeutic agents where halogen substitution patterns are critical for binding affinity. The compound participates effectively in nucleophilic substitution reactions and cross-coupling processes, enabling chemists to introduce specific functional groups with high regioselectivity.

Beyond pharmaceuticals, this intermediate finds utility in the development of advanced agrochemicals and specialty materials. The stability of the carbon-fluorine bond contributes to the durability and performance of final products in challenging environmental conditions. Researchers utilize this building block to explore structure-activity relationships, optimizing lead compounds for improved efficacy and safety profiles. Its compatibility with standard laboratory reagents simplifies process development and scale-up activities.

Quality Assurance and Logistics

We maintain a robust quality management system to ensure product consistency from synthesis to delivery. Each shipment is accompanied by a Certificate of Analysis (COA) detailing test results against established specifications. Our packaging options include 25 kg drums, with flexibility to accommodate custom requirements for bulk orders. Proper storage in a cool and ventilated environment preserves the integrity of the material during transit and warehousing.

As a global manufacturer, we prioritize reliable supply chain management to prevent production delays. Our logistics network supports international shipping with compliance to all relevant safety regulations. Technical support is available to assist with application guidance and troubleshooting. Partnering with us provides access to high-performance chemical intermediates backed by decades of industry expertise and a commitment to customer success.