Intermediates

2-Chloro-4-Fluoropyridine

  • CAS No.34941-91-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Chloro-4-Fluoropyridine (CAS 34941-91-8) designed for advanced pharmaceutical synthesis. Available in bulk quantities with strict quality control.

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Product Technical Details

Product Overview

2-Chloro-4-Fluoropyridine is a highly valued heterocyclic building block extensively utilized in modern organic synthesis and medicinal chemistry. As a dihalogenated pyridine derivative, this compound offers unique reactivity profiles due to the presence of both chlorine and fluorine substituents on the pyridine ring. Our manufacturing process ensures exceptional purity levels, making it an ideal candidate for complex pharmaceutical intermediate production and agrochemical development.

The strategic positioning of halogen atoms allows for selective nucleophilic substitution reactions, enabling chemists to construct sophisticated molecular architectures with high precision. This versatility makes it a cornerstone reagent in the discovery and development of new therapeutic agents.

Key Specifications

ParameterValue
Chemical Name2-Chloro-4-Fluoropyridine
CAS Number34941-91-8
Molecular FormulaC5H3ClFN
Molecular Weight131.54 g/mol
AppearanceYellow liquid
Purity≥99.0%
Boiling Point157.9±20.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Refractive Index1.503

Industrial Applications

This compound serves as a critical precursor in the synthesis of various biologically active molecules. Its primary applications include:

  • Pharmaceutical Intermediate Synthesis: Used extensively in the production of kinase inhibitors and other targeted therapies.
  • Agrochemical Development: Acts as a key building block for novel pesticides and herbicides requiring heterocyclic structures.
  • Material Science: Employed in the creation of specialized polymers and organic electronic materials.
  • Cross-Coupling Reactions: Suitable for Suzuki, Heck, and Sonogashira coupling reactions due to its halogen activation properties.

Quality Assurance And Safety

We adhere to strict quality management systems to guarantee consistency across all batches. Every shipment is accompanied by a comprehensive Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS). Our facilities maintain optimal storage conditions to preserve chemical integrity during warehousing and transit.

For safe handling, store in a tightly closed container within a cool, dry environment away from incompatible materials. Proper ventilation and personal protective equipment are recommended during laboratory or industrial use. Contact our technical sales team for detailed safety protocols and bulk pricing information tailored to your specific production needs.