Intermediates

2-Chloro-4-hydroxypyridine

  • CAS No.17368-12-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Chloro-4-hydroxypyridine (CAS 17368-12-6) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical intermediates.

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Product Technical Details

Product Overview

2-Chloro-4-hydroxypyridine is a highly valued heterocyclic compound widely utilized in the field of fine chemical synthesis and pharmaceutical manufacturing. As a crucial pyridine derivative, this substance serves as a fundamental building block for constructing more complex molecular architectures. Our facility specializes in the production of this intermediate with strict adherence to international quality standards, ensuring consistency and reliability for downstream applications. The compound is characterized by its stable chemical structure and high reactivity at specific positions, making it an ideal candidate for nucleophilic substitution reactions and various coupling processes.

We understand the critical nature of raw material quality in the production of active pharmaceutical ingredients (APIs) and agrochemicals. Therefore, every batch of 2-Chloro-4-hydroxypyridine undergoes rigorous analytical testing to confirm identity and purity. Our commitment to excellence ensures that clients receive a product that meets the demanding specifications required for modern medicinal chemistry and industrial organic synthesis.

Technical Specifications

The following table outlines the key physical and chemical properties of our standard grade product. These parameters are verified through advanced instrumentation including HPLC, NMR, and mass spectrometry to guarantee accuracy.

ParameterSpecification
CAS Number17368-12-6
Molecular FormulaC5H4ClNO
Molecular Weight129.544 g/mol
AppearanceWhite to off-white crystalline powder
Assay (Purity)≥98.0%
Melting Point169-172°C
Boiling Point401.8±25.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point196.8±23.2 °C

Industrial Applications

This chemical intermediate finds extensive utility across multiple sectors of the chemical industry. Its primary role involves serving as a precursor in the synthesis of various pharmacologically active compounds. The chloro and hydroxy functional groups provide versatile handles for further chemical modification, allowing chemists to introduce diverse substituents onto the pyridine ring.

  • Pharmaceutical Intermediate: Used in the development of novel drug candidates targeting various therapeutic areas.
  • Agrochemical Synthesis: Employed in the creation of herbicides and pesticides requiring pyridine scaffolds.
  • Material Science: Utilized in the preparation of specialized polymers and functional materials.
  • Research and Development: Essential reagent for academic and industrial laboratories focusing on heterocyclic chemistry.

Quality Assurance and Safety

Quality control is paramount in our manufacturing process. We implement a comprehensive quality management system that monitors every stage of production, from raw material sourcing to final packaging. Each shipment is accompanied by a Certificate of Analysis (COA) that details the test results for purity, moisture content, and impurity profiles. This transparency allows our partners to maintain their own quality standards without compromise.

Safety is equally critical when handling chemical intermediates. 2-Chloro-4-hydroxypyridine should be handled in a well-ventilated environment with appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a cool, dry, and ventilated place away from incompatible substances. Our packaging is designed to prevent moisture absorption and contamination during transit, ensuring the product arrives in optimal condition.

Packaging and Logistics

We offer flexible packaging solutions to meet the diverse needs of our global clientele. The standard packaging configuration is 25 kg per drum, which provides excellent protection and ease of handling. For larger volume requirements, we can customize packaging according to specific customer requests. Our logistics network ensures timely delivery worldwide, supported by robust documentation for customs clearance and regulatory compliance. Partner with us for a reliable supply chain of high-quality chemical intermediates.