2-Chloro-4-iodopyridine
- CAS No.153034-86-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Chloro-4-iodopyridine (CAS 153034-86-7) is a premium pyridine derivative designed for complex organic synthesis and pharmaceutical manufacturing processes.
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Product Overview
2-Chloro-4-iodopyridine is a highly valued halogenated pyridine derivative extensively utilized in modern medicinal chemistry and advanced organic synthesis. As a key heterocyclic building block, this compound features distinct reactivity profiles due to the presence of both chloro and iodo substituents on the pyridine ring. Our manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal choice for researchers and industrial chemists seeking reliable raw materials for complex molecular constructions.
We understand the critical nature of purity in multi-step synthesis routes. Therefore, our production facilities adhere to strict quality management systems to deliver material that meets rigorous analytical standards. This product serves as a versatile intermediate for developing novel pharmaceutical agents, agrochemicals, and functional materials.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2-Chloro-4-iodopyridine |
| CAS Number | 153034-86-7 |
| Molecular Formula | C5H3ClIN |
| Molecular Weight | 239.44 g/mol |
| Appearance | Off-white to white crystalline powder |
| Purity (GC) | ≥99.0% |
| Melting Point | 42-43°C |
| Boiling Point | 255.5°C |
| Density | 2.052 g/cm³ |
| Refractive Index | 1.642 |
Industrial Applications
The unique substitution pattern of 2-Chloro-4-iodopyridine allows for selective cross-coupling reactions, enabling chemists to functionalize the pyridine core with high precision. The iodine atom typically exhibits higher reactivity in palladium-catalyzed coupling reactions compared to the chlorine atom, providing a strategic handle for sequential synthesis. This characteristic is particularly valuable in the construction of kinase inhibitors and other biologically active molecules where the pyridine scaffold is prevalent.
Beyond pharmaceuticals, this intermediate finds application in the synthesis of advanced polymers and liquid crystal materials. Its stability and reactivity balance make it suitable for large-scale manufacturing processes where safety and efficiency are paramount. Our team provides comprehensive technical support to assist clients in optimizing their synthesis routes using this building block.
Quality Assurance and Packaging
Quality control is integral to our operation. Each batch undergoes thorough analysis using gas chromatography and other advanced spectroscopic methods to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to ensure transparency and compliance with your internal quality standards. We maintain industrial purity levels to minimize downstream purification burdens.
Standard packaging consists of 25 kg drums, designed to protect the material from moisture and light during transit. Custom packaging solutions are available upon request to accommodate specific logistical requirements. Proper storage in a cool, ventilated area ensures the long-term stability of the product. As a global manufacturer, we are committed to reliable supply chains and timely delivery to support your production schedules.
