Intermediates

2-Chloro-4-methoxy-3-nitropyridine

  • CAS No.6980-09-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Chloro-4-methoxy-3-nitropyridine intermediate designed for advanced organic synthesis and pharmaceutical building block applications.

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Product Technical Details

Product Overview

2-Chloro-4-methoxy-3-nitropyridine is a highly specialized heterocyclic compound that serves as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern on the pyridine ring, this chemical intermediate offers exceptional reactivity for nucleophilic aromatic substitution reactions. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for research and development teams working on complex pharmaceutical agents and agrochemical formulations.

The presence of both chloro and nitro functional groups on the pyridine backbone provides versatile sites for chemical modification. This versatility allows chemists to construct diverse molecular architectures efficiently. As a trusted global manufacturer, we prioritize strict quality control measures to deliver materials that meet the rigorous demands of industrial-scale synthesis and laboratory research.

Technical Specifications

ParameterValue
CAS Number6980-09-2
Molecular FormulaC6H5ClN2O3
Molecular Weight188.568 g/mol
AppearanceYellow crystalline powder
Assay (Purity)≥98.0%
Density1.4±0.1 g/cm3
Boiling Point314.9±37.0 °C at 760 mmHg
Flash Point144.3±26.5 °C
Refractive Index1.565

Industrial Applications

This pyridine derivative is extensively utilized in the preparation of advanced pharmaceutical intermediates. The electron-withdrawing nature of the nitro group activates the ring towards nucleophilic attack, facilitating the introduction of various amines, thiols, or alkoxides at the chloro position. This reactivity profile is essential for developing kinase inhibitors, antiviral agents, and other therapeutic compounds where pyridine scaffolds are prevalent.

Beyond pharmaceuticals, this compound finds application in the synthesis of specialized agrochemicals and functional materials. Researchers value its stability under standard storage conditions and its predictable behavior during multi-step synthesis routes. Whether used in process development or scale-up production, 2-Chloro-4-methoxy-3-nitropyridine provides a reliable foundation for creating high-value chemical entities.

Quality Assurance and Handling

Every batch produced undergoes comprehensive analytical testing to verify identity and purity. We provide a Certificate of Analysis (COA) with each shipment, detailing specific test results against our internal specifications. Our facility adheres to international safety standards to ensure the integrity of the product from synthesis to delivery.

  • Packaged in 25 kg drums or according to specific customer requirements.
  • Stored in a cool, ventilated area away from direct sunlight and moisture.
  • Compatible with standard chemical handling protocols for nitro-containing compounds.
  • Global shipping capabilities ensure timely delivery to research and production sites.

For technical inquiries or bulk pricing requests, our sales team is ready to assist with customized solutions tailored to your project needs. We are committed to supporting innovation in the chemical industry through reliable supply chains and premium quality intermediates.