Intermediates

2-Chloro-4-nitropyridine

  • CAS No.23056-36-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Chloro-4-nitropyridine (CAS 23056-36-2) designed for advanced organic synthesis. Reliable supply with strict quality control for global pharmaceutical and chemical manufacturing.

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Product Technical Details

Product Overview

2-Chloro-4-nitropyridine represents a critical heterocyclic building block extensively utilized in modern organic synthesis and chemical manufacturing. As a chlorinated nitropyridine derivative, this compound features a pyridine ring substituted with both chloro and nitro functional groups, enabling versatile chemical transformations. Our manufacturing process ensures high consistency and purity, making it an ideal choice for research and industrial scale production. The presence of the electron-withdrawing nitro group activates the ring towards nucleophilic aromatic substitution, facilitating the development of complex molecular structures required in pharmaceutical and agrochemical industries.

We are committed to supplying premium quality chemical intermediates that meet rigorous international standards. Each batch undergoes strict quality control protocols to verify identity and purity. This product is particularly valued for its reactivity profile, allowing chemists to introduce nitrogen-containing heterocycles into target molecules efficiently. Whether used in laboratory-scale discovery or large-scale manufacturing, our 2-Chloro-4-nitropyridine provides a reliable foundation for synthetic pathways. We prioritize safety and compliance in all production stages.

Technical Specifications

The following table outlines the key physical and chemical properties of our standard grade material. These parameters are critical for process engineers and chemists to ensure compatibility with downstream reactions and safety handling procedures. Our quality assurance team verifies every parameter before shipment.

ParameterValue
CAS Number23056-36-2
Molecular FormulaC5H3ClN2O2
Molecular Weight158.54 g/mol
AppearanceYellow Powder
Assay (Purity)≥ 98.0%
Melting Point52-56 °C
Boiling Point258.4 °C
Density1.489 g/cm3
Flash Point223 °F

Industrial Applications

This compound serves as a versatile intermediate in the synthesis of various fine chemicals. Its primary application lies in the production of pharmaceutical active ingredients where pyridine scaffolds are required. The chloro group acts as a leaving group for substitution reactions with amines, thiols, or alkoxides, while the nitro group can be reduced to an amine for further functionalization. Additionally, it is employed in the agrochemical sector for developing novel pesticides and herbicides. The high purity specification ensures minimal side reactions, improving overall yield and reducing purification costs in multi-step synthesis.

  • Pharmaceutical intermediate for heterocyclic drug synthesis.
  • Agrochemical building block for pesticide development.
  • Reagent for nucleophilic aromatic substitution reactions.
  • Material science applications involving functionalized pyridines.
  • Custom synthesis projects requiring high purity starting materials.

Safety and Storage

Proper handling is essential to maintain product integrity and ensure workplace safety. The material should be stored in a cool, well-ventilated area away from direct sunlight and moisture. Containers must be kept tightly closed when not in use to prevent degradation. We recommend using appropriate personal protective equipment during handling. Our packaging options include 25 kg drums, with customization available to meet specific logistical requirements. Global shipping is supported with comprehensive documentation, including Certificates of Analysis and Safety Data Sheets. Contact our technical team for detailed handling guidelines.