Intermediates

2-Chloro-5-(chloromethyl)thiazole

  • CAS No.105827-91-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Chloro-5-(chloromethyl)thiazole intermediate for agrochemical and pharmaceutical synthesis. Available in bulk with comprehensive COA.

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Product Technical Details

Product Overview

2-Chloro-5-(chloromethyl)thiazole is a highly versatile organic intermediate widely utilized in the synthesis of advanced agrochemicals and pharmaceutical compounds. As a critical building block, this thiazole derivative plays an essential role in the manufacturing process of neonicotinoid insecticides and specific antiviral pharmaceutical intermediates. Our facility ensures strict quality control standards to deliver consistent molecular integrity for large-scale industrial applications.

Manufactured under rigorous safety protocols, this chemical reagent is designed for professional laboratory and production environments. The compound features a stable thiazole ring structure with reactive chloromethyl functionality, enabling efficient nucleophilic substitution reactions required for complex organic synthesis pathways.

Key Specifications

ParameterSpecification
Chemical Name2-Chloro-5-(chloromethyl)thiazole
CAS Number105827-91-6
Molecular FormulaC4H3Cl2NS
Molecular Weight168.04 g/mol
AppearanceColorless or light yellow transparent liquid or crystal
Assay (Purity)≥98.0%
Moisture Content≤0.05%
Density1.503 g/cm3
Melting Point31°C
Boiling Point268.6°C
Flash Point116.3°C
Refractive Index1.583

Industrial Applications

This intermediate is primarily employed in the production of high-efficiency neonicotinoid insecticides such as thiamethoxam and clothianidin. These agrochemicals are vital for modern crop protection strategies, requiring precise precursor quality to ensure final product efficacy. Additionally, the compound serves as a key precursor in the synthesis of pharmaceutical intermediates, including those used in antiviral medication development.

  • Agrochemical Synthesis: Essential for neonicotinoid insecticide manufacturing.
  • Pharmaceutical Intermediates: Used in constructing complex heterocyclic drug structures.
  • Organic Research: Valuable reagent for heterocyclic chemistry studies.
  • Custom Synthesis: Adaptable for various chloromethyl substitution reactions.

Quality Assurance and Packaging

We prioritize product stability and safety during transit. Each batch undergoes comprehensive analytical testing, including HPLC and GC analysis, to verify purity levels meet or exceed industry standards. A Certificate of Analysis (COA) is provided with every shipment to guarantee compliance with your quality requirements.

Standard packaging includes 25 kg drums, securely sealed to prevent moisture absorption and contamination. Custom packaging solutions are available upon request to accommodate specific logistical needs. Storage recommendations include keeping the container in a cool, ventilated area away from direct sunlight and incompatible materials to maintain optimal chemical stability.