Intermediates

2-Chloro-5-fluoro-3-methylpyridine

  • CAS No.38186-84-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Chloro-5-fluoro-3-methylpyridine (CAS 38186-84-4) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and agrochemical applications.

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Product Technical Details

Product Overview

2-Chloro-5-fluoro-3-methylpyridine is a highly specialized fluorinated heterocyclic compound that serves as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern on the pyridine ring, this molecule offers exceptional reactivity for nucleophilic aromatic substitution and cross-coupling reactions. Our facility produces this intermediate under strict quality control protocols to ensure consistent performance in downstream chemical processes. As a key supplier in the fine chemicals sector, we understand the demanding requirements of pharmaceutical and agrochemical research teams.

The introduction of fluorine atoms into organic molecules is a strategic approach in modern drug design, often enhancing metabolic stability and bioavailability. Consequently, 2-Chloro-5-fluoro-3-methylpyridine is sought after for its ability to impart these desirable characteristics to final products. The methyl group at the 3-position adds steric and electronic properties that can significantly influence the biological activity of the final target molecule. We are committed to providing this material with high chemical purity to minimize impurities that could affect reaction yields or complicate purification steps. Our manufacturing capabilities allow us to scale production to meet both research-scale needs and large-scale industrial demands without compromising on quality.

Technical Specifications

Our production process guarantees that every batch meets rigorous analytical standards. The following table outlines the key physical and chemical properties verified by our quality assurance team. Customers can rely on these specifications for their process development and scale-up activities. We utilize advanced chromatography and spectroscopy methods to confirm identity and purity levels before release.

ParameterValue
CAS Number38186-84-4
Molecular FormulaC6H5ClFN
Molecular Weight145.562 g/mol
AppearanceWhite solid
Assay≥98.0%
Boiling Point177.9±35.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point61.4±25.9 °C

Industrial Applications

This fluorinated pyridine derivative is predominantly utilized as an intermediate in the synthesis of complex organic molecules. Its primary applications span across the pharmaceutical industry, where it is incorporated into drug candidates targeting various therapeutic areas. The chemical stability of the carbon-fluorine bond combined with the reactivity of the carbon-chlorine bond allows for selective transformations. In agrochemical formulations, this compound contributes to the efficacy of crop protection agents. The specific arrangement of substituents allows for tailored interactions with biological targets.

  • Pharmaceutical API Synthesis: Used as a core scaffold for developing new medications.
  • Agrochemical Development: Employed in the creation of advanced pesticides and herbicides.
  • Material Science: Utilized in the preparation of specialized functional materials.
  • Research and Development: Essential for academic and industrial laboratory experiments.

Quality Assurance and Logistics

We prioritize the integrity of our supply chain to ensure timely delivery of 2-Chloro-5-fluoro-3-methylpyridine. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing the test results for purity and identity. The product is packaged in 25 kg drums, though we offer flexible packaging solutions to accommodate specific customer requirements. Proper storage in a cool, ventilated area is recommended to maintain product stability over time. Handling requires standard laboratory safety precautions including the use of personal protective equipment. Safety data sheets (SDS) are provided with every order to ensure compliant handling within your facility. We adhere to international shipping regulations for chemical goods, ensuring that your procurement process is smooth and hassle-free. Our team provides technical support to assist with integration into your manufacturing processes.