Intermediates

2-Chloro-5-fluoro-6-methylpyridine

  • CAS No.884494-78-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Chloro-5-fluoro-6-methylpyridine (CAS 884494-78-4) designed for advanced pharmaceutical synthesis. Available in bulk quantities with strict quality control.

Request Bulk Pricing

Product Technical Details

Product Overview

2-Chloro-5-fluoro-6-methylpyridine is a specialized heterocyclic compound that serves as a critical building block in modern medicinal chemistry and organic synthesis. As a fluorinated pyridine derivative, this chemical intermediate offers unique reactivity profiles that are essential for constructing complex molecular architectures. Our facility produces this compound under stringent quality management systems to ensure consistency and reliability for downstream pharmaceutical applications.

The presence of both chloro and fluoro substituents on the pyridine ring provides versatile sites for nucleophilic substitution and cross-coupling reactions. This makes the material particularly valuable for researchers and industrial manufacturers developing new therapeutic agents. We understand the critical nature of supply chain stability in the pharmaceutical sector, which is why we maintain robust inventory levels and streamlined logistics capabilities.

Key Specifications

Quality is the cornerstone of our manufacturing process. Each batch undergoes rigorous analytical testing to verify compliance with established specifications. The following table outlines the typical physical and chemical properties associated with this product grade.

ParameterSpecification
CAS Number884494-78-4
Molecular FormulaC6H5ClFN
Molecular Weight145.56 g/mol
AppearanceWhite Crystalline Powder
Purity≥99.0%
Melting Point58-60°C
Boiling Point163.4±35.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Refractive Index1.504

Industrial Applications

This fluorinated intermediate is primarily utilized in the synthesis of pharmaceutical active ingredients. Its structural characteristics allow for precise functionalization, enabling chemists to introduce specific pharmacophores into drug candidates. Common applications include serving as a precursor in the development of kinase inhibitors and other targeted therapies where halogenated pyridines are required.

Beyond pharmaceuticals, this compound may find utility in agrochemical research and material science where modified pyridine structures are needed. The high purity level ensures minimal side reactions during synthesis, improving overall yield and reducing purification burdens in multi-step processes. Our technical team is available to provide guidance on optimal usage conditions for specific synthetic routes.

Quality Assurance and Packaging

We are committed to delivering products that meet international standards. Every shipment is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. Our packaging solutions are designed to maintain product integrity during transit. Standard packing consists of 25 KGS per drum, utilizing materials that protect against moisture and physical damage. Custom packaging configurations are available upon request for large-scale industrial orders.

Storage and Handling

Proper storage is essential to maintain the stability of 2-Chloro-5-fluoro-6-methylpyridine. The product should be stored in a tightly closed container in a cool, dry, and well-ventilated area. Avoid exposure to direct sunlight and sources of ignition. When handling this material, appropriate personal protective equipment including gloves and safety goggles should be worn to prevent skin and eye contact. Adherence to standard laboratory safety protocols ensures a safe working environment for all personnel involved in the handling of this chemical intermediate.