2-Chloro-5-fluorobenzoic acid
- CAS No.2252-50-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Chloro-5-fluorobenzoic acid designed for advanced organic synthesis and pharmaceutical intermediate manufacturing.
Request Bulk PricingProduct Technical Details
Product Overview
2-Chloro-5-fluorobenzoic acid represents a critical halogenated aromatic building block extensively utilized within the fine chemical and pharmaceutical sectors. This specialized organic compound features a benzoic acid backbone substituted with both chloro and fluoro groups, providing unique reactivity profiles essential for complex molecular construction. Our manufacturing process ensures consistent quality, making it an ideal choice for researchers and industrial chemists seeking reliable raw materials for multi-step synthesis pathways.
The strategic positioning of the halogen atoms allows for selective functionalization, enabling chemists to perform targeted coupling reactions. As a key intermediate, it serves as a precursor for various agrochemicals, pharmaceuticals, and advanced materials. The stability of the carbon-halogen bonds under standard conditions facilitates safe handling and storage, while still remaining reactive under catalytic conditions required for modern organic synthesis.
Technical Specifications
Quality control is paramount in our production facility. Each batch undergoes rigorous analytical testing to verify identity and purity levels. The physical characteristics are consistent with high-grade laboratory and industrial standards. Below are the detailed technical parameters associated with this product grade.
| Parameter | Value |
|---|---|
| CAS Number | 2252-50-8 |
| Molecular Formula | C7H4ClFO2 |
| Molecular Weight | 174.56 g/mol |
| Appearance | White to off-white powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 147-149°C |
| Boiling Point | 275.3°C |
| Density | 1.477 g/cm3 |
Industrial Applications
This compound is primarily deployed as a versatile intermediate in the synthesis of active pharmaceutical ingredients (APIs). The presence of the carboxylic acid group allows for conversion into esters, amides, or acid chlorides, expanding its utility in medicinal chemistry campaigns. Furthermore, the halogen substituents enable cross-coupling reactions such as Suzuki or Buchwald-Hartwig couplings, which are fundamental in constructing biaryl structures common in drug candidates.
Beyond pharmaceuticals, this chemical finds application in the development of novel agrochemical formulations and functional materials. Its specific electronic properties contribute to the performance of downstream products, making it a valuable component in research and development pipelines focused on innovation and efficiency. Additionally, the compound is utilized in the synthesis of liquid crystals and polymers where specific thermal stability is required. The fluorine atom imparts lipophilicity and metabolic stability to resulting molecules, a highly sought-after trait in modern drug design.
Quality Assurance and Handling
We adhere to strict safety and quality management systems. All products are packaged in secure containers to prevent contamination during transit. Standard packaging includes 25 kg drums, though custom solutions are available to meet specific logistical requirements. Storage recommendations include keeping the material in a cool, ventilated area away from incompatible substances to maintain integrity over time.
Documentation such as Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS) are provided with every shipment. Our global supply chain ensures timely delivery to partners worldwide, supported by a dedicated technical team ready to assist with application-specific inquiries. Our commitment to excellence extends beyond mere compliance. We implement traceability protocols for every production lot, ensuring that any query can be resolved with precise data. Customer satisfaction is driven by our ability to provide consistent batch-to-batch reproducibility, which is critical for scaling up processes from laboratory bench to commercial manufacturing.
