2-Chloro-5-(trifluoromethyl)phenol
- CAS No.40889-91-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2-Chloro-5-(trifluoromethyl)phenol (CAS 40889-91-6) designed for advanced organic synthesis. Reliable supply with strict quality control for global pharmaceutical and chemical manufacturing.
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Product Overview
We are pleased to present our premium grade 2-Chloro-5-(trifluoromethyl)phenol, a high-value fluorinated intermediate essential for modern organic synthesis. This specialized chemical compound is meticulously manufactured to meet the rigorous demands of pharmaceutical research, agrochemical development, and advanced material science applications. As a leading global manufacturer, we ensure that every batch undergoes strict quality assurance protocols to guarantee consistency and reliability for your production processes.
The unique structural configuration of this molecule, featuring both chloro and trifluoromethyl substituents on the phenolic ring, provides exceptional reactivity profiles. The presence of the trifluoromethyl group is particularly significant in medicinal chemistry, as it often enhances the lipophilicity, metabolic stability, and bioavailability of downstream drug candidates. Our commitment to excellence ensures that this intermediate serves as a robust building block for complex molecular architectures.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2-Chloro-5-(trifluoromethyl)phenol |
| CAS Number | 40889-91-6 |
| Molecular Formula | C7H4ClF3O |
| Molecular Weight | 196.554 g/mol |
| Appearance | Light yellow oily liquid |
| Assay (Purity) | ≥98.0% |
| Boiling Point | 171.3±0.0 °C at 760 mmHg |
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 46.1±0.0 °C |
| Refractive Index | 1.482 |
Industrial Applications
This fluorinated phenol derivative is primarily utilized as a key intermediate in the synthesis of various fine chemicals. Its versatile reactivity allows it to participate in a wide range of organic transformations, including nucleophilic aromatic substitution and etherification reactions. The chloro substituent offers a strategic handle for further functionalization, making it an invaluable precursor in multi-step synthesis routes.
- Pharmaceutical Industry: Used in the development of novel therapeutic agents where fluorine substitution is required to optimize pharmacokinetic properties.
- Agrochemical Sector: Serves as a building block for creating high-performance pesticides and herbicides with enhanced environmental stability.
- Material Science: Applied in the synthesis of specialized polymers and liquid crystals requiring specific electronic or thermal characteristics.
- Custom Synthesis: Available for bespoke research projects requiring high-purity starting materials for method development.
Quality Assurance and Handling
Safety and quality are paramount in our operations. Each shipment of 2-Chloro-5-(trifluoromethyl)phenol is accompanied by a comprehensive Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS). Our manufacturing facilities adhere to international safety standards, ensuring that the product is free from contaminants and meets the specified assay requirements.
For storage, we recommend keeping the material in a cool, ventilated place away from direct sunlight and incompatible substances. The product is packaged in secure 200 kg drums to prevent leakage and contamination during transit. However, we also offer flexible packaging solutions tailored to specific customer requirements. Our logistics team ensures global shipping capabilities, delivering your order safely and on time. For bulk pricing inquiries or technical support regarding synthesis routes, please contact our sales team directly.
