Intermediates

2-Chloroacrylonitrile

  • CAS No.920-37-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Chloroacrylonitrile (CAS 920-37-6), a key chemical intermediate for agrochemical and pharmaceutical synthesis.

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Product Technical Details

Product Overview

2-Chloroacrylonitrile (CAS 920-37-6) is a versatile organic building block widely employed in the synthesis of advanced agrochemicals and active pharmaceutical ingredients. This colorless to light yellow liquid features high reactivity due to its conjugated nitrile and vinyl chloride functionalities, making it an essential precursor in multi-step synthetic pathways.

Specifications

Molecular FormulaC₃H₂ClN
Molecular Weight87.508 g/mol
AppearanceColorless or light yellow liquid
Assay≥99.0%
Water Content≤0.5%
Boiling Point89.5 ± 13.0 °C at 760 mmHg
Melting Point−65 °C (lit.)
Density1.1 ± 0.1 g/cm³
Flash Point6.7 ± 0.0 °C
Vapour Pressure58.4 ± 0.2 mmHg at 25 °C
Refractive Index1.435
LogP0.34

Industrial Applications

As a critical intermediate in fine chemical manufacturing, 2-Chloroacrylonitrile serves as a foundational component in the production of several high-value compounds:

  • Key intermediate for Thifensulfuron-methyl (CAS 79277-67-1), a sulfonylurea herbicide.
  • Essential building block in the synthesis of Chlorfenapyr (CAS 122453-73-0), a broad-spectrum insecticide and acaricide.
  • Used in the development of arylpyrrole-based fungicides and insecticides, including Bromopyronil analogs.
  • Applied in pharmaceutical R&D for antirheumatic agents and certain neuroactive compound scaffolds under strict regulatory compliance.
  • Utilized in the preparation of specialty photosensitive materials for electronic and imaging applications.

Due to its reactive nature, this compound must be handled with appropriate safety protocols and stored in tightly sealed containers in a cool, dry, and well-ventilated environment. Standard packaging is 25 kg per drum, with custom configurations available upon request.