Intermediates

2-Chlorobenzotrifluoride

  • CAS No.88-16-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Chlorobenzotrifluoride (CAS 88-16-4) supplied for agricultural and pharmaceutical synthesis. Reliable quality with comprehensive COA.

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Product Technical Details

Product Overview

2-Chlorobenzotrifluoride represents a cornerstone molecule in the realm of fluorinated organic chemistry. This colorless liquid is characterized by its distinct chemical stability and reactivity, making it an indispensable raw material for the synthesis of advanced functional materials. As a global manufacturer, we understand the critical need for consistency in chemical supply chains. Our production facilities utilize state-of-the-art technology to ensure that every batch of 2-Chlorobenzotrifluoride meets stringent international quality standards.

The molecular structure features a benzene ring substituted with both chlorine and trifluoromethyl groups at ortho positions. This specific arrangement imparts unique electronic properties that are highly valued in medicinal chemistry and agrochemical design. The trifluoromethyl group is particularly noted for enhancing the lipophilicity and metabolic stability of downstream products, which is why this intermediate is sought after for high-performance applications.

Technical Specifications

Transparency in product specifications is vital for our industrial partners. The data below reflects the typical properties of our high-purity grade. These values are determined using calibrated analytical instruments to ensure accuracy and reproducibility across different lots.

ParameterValue
CAS Number88-16-4
Molecular FormulaC7H4ClF3
Molecular Weight180.555
AppearanceColorless transparent liquid
Assay≥99.0%
Density1.379 g/cm³
Boiling Point152 ºC
Melting Point-7.4 °C
Refractive Index1.455-1.457
Flash Point44 ºC
Water Solubility<0.1 g/100 mL

Industrial Applications

The versatility of 2-Chlorobenzotrifluoride allows it to serve multiple sectors within the chemical industry. Its primary application lies in the agrochemical sector, where it acts as a key precursor for various pest management solutions. The compound is specifically utilized in the synthesis of intermediates for rodenticides and other crop protection agents, contributing to global food security efforts.

In the pharmaceutical industry, fluorinated intermediates are increasingly important for developing new therapeutic agents. This product serves as a building block for creating complex molecules with improved pharmacokinetic profiles. Researchers utilize this compound to introduce fluorine atoms into drug candidates, a strategy known to improve binding affinity and resistance to enzymatic degradation.

  • Synthesis of agrochemical intermediates and pest control agents.
  • Development of pharmaceutical active ingredients (APIs).
  • Production of fine organic chemicals and specialized polymers.
  • Use in organic synthesis reactions requiring nucleophilic substitution.
  • Manufacturing of liquid crystals and electronic chemicals.

Quality Assurance and Safety

Our commitment to quality extends beyond the final product. We implement a comprehensive Quality Management System (QMS) that monitors every step of the manufacturing process. From raw material sourcing to final packaging, each stage is subject to rigorous testing using advanced chromatography and spectroscopy methods. Customers receive a detailed Certificate of Analysis (COA) with every order, providing full traceability and confidence in the material's purity and identity.

Safety is paramount in handling chemical intermediates. 2-Chlorobenzotrifluoride is flammable and should be stored in a cool, well-ventilated place away from incompatible substances such as strong oxidizers and bases. Containers must remain tightly closed to prevent moisture uptake and vapor release. We offer flexible packaging solutions, typically 25kg drums, but can accommodate specific customer requirements to optimize logistics and storage efficiency. Partnering with us ensures a reliable supply of high-quality chemicals for your industrial needs. Our logistics team ensures compliant shipping documentation for global delivery.