(2-Chloroethyl)benzene
- CAS No.622-24-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity (2-Chloroethyl)benzene (CAS 622-24-2), a key chlorinated aromatic intermediate for advanced organic synthesis and pharmaceutical manufacturing.
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Product Overview
(2-Chloroethyl)benzene, also known as phenethyl chloride or benzene, (2-chloroethyl)-, is a versatile chlorinated aromatic compound widely employed as a building block in fine chemical and pharmaceutical synthesis. With the molecular formula C8H9Cl and a molecular weight of 140.61 g/mol, this reagent serves as a critical intermediate in multi-step synthetic pathways, particularly in the construction of complex bioactive molecules.
Specifications
| Molecular Formula | C8H9Cl |
|---|---|
| Molecular Weight | 140.61 g/mol |
| Density | 1.069 g/cm³ |
| Melting Point | -60 °C |
| Boiling Point | 82–84 °C |
| Flash Point | 152 °F (67 °C) |
| Refractive Index | 1.53 |
| Appearance | Colorless to slightly yellow transparent liquid |
| Purity (GC) | ≥99% |
| Moisture Content | ≤0.1% |
Industrial Applications
This compound functions primarily as a synthetic intermediate in the production of active pharmaceutical ingredients (APIs) and specialty chemicals. It is notably utilized in the synthesis of immunomodulatory agents and other complex neurological therapeutics through well-established alkylation and nucleophilic substitution protocols. Its reactive chloroethyl group enables efficient carbon-chain extension and heterocycle formation under controlled conditions.
- Serves as a precursor in multi-step API syntheses
- Enables introduction of phenethyl motifs into molecular scaffolds
- Compatible with standard organometallic and polar reaction conditions
- Supplied in high industrial purity for consistent batch performance
Stored in a cool, well-ventilated area away from heat and incompatible materials, (2-Chloroethyl)benzene is typically packed in 200 kg steel drums or customized containers per client specifications. All batches are accompanied by a comprehensive Certificate of Analysis (COA) to ensure traceability and compliance with global regulatory standards.
