Intermediates

2-Chlorophenylboronic acid

  • CAS No.3900-89-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Chlorophenylboronic acid (CAS 3900-89-8) designed for advanced pharmaceutical synthesis. Reliable bulk supply with strict quality control.

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Product Technical Details

Product Overview

2-Chlorophenylboronic acid represents a critical organoboron compound extensively utilized in modern organic synthesis and medicinal chemistry. As a versatile building block, this substance plays a pivotal role in facilitating carbon-carbon bond formation through palladium-catalyzed cross-coupling reactions. Our manufacturing process ensures that every batch meets rigorous international standards for purity and consistency, making it an ideal choice for research laboratories and industrial production facilities alike.

The chemical structure features a chloro substituent at the ortho position of the phenyl ring attached to the boronic acid group. This specific configuration enhances its reactivity in Suzuki-Miyaura coupling reactions, allowing chemists to construct complex biaryl structures efficiently. Due to its stability and manageable handling properties, it has become a staple reagent in the development of novel active pharmaceutical ingredients and advanced material sciences.

Technical Specifications

ParameterValue
CAS Number3900-89-8
Molecular FormulaC6H6BClO2
Molecular Weight156.38 g/mol
AppearanceWhite powder
Assay≥98.0%
Water Content≤0.50%
Melting Point92-102 °C
Boiling Point306.3 °C at 760 mmHg
Density1.32 g/cm3
Flash Point139 °C

Industrial Applications

The primary application of this boronic acid derivative lies within the pharmaceutical sector, where it serves as a key intermediate for synthesizing diverse therapeutic compounds. Its ability to participate in cross-coupling reactions enables the creation of complex molecular architectures required for drug discovery programs. Beyond pharmaceuticals, it finds utility in the agrochemical industry for developing crop protection agents and in the materials science field for producing organic electronic components.

  • Essential reagent for Suzuki-Miyaura cross-coupling reactions
  • Building block for biaryl synthesis in drug development
  • Used in the production of agrochemical intermediates
  • Applicable in organic light-emitting diode (OLED) material synthesis
  • Supports custom synthesis projects for specialized research needs

Quality Assurance and Storage

We maintain a comprehensive quality management system to guarantee the reliability of our chemical products. Each production lot undergoes strict analytical testing using high-performance liquid chromatography and nuclear magnetic resonance spectroscopy to verify identity and purity. A Certificate of Analysis is provided with every shipment to ensure transparency and compliance with customer specifications.

Proper storage is essential to maintain the integrity of the product. It should be kept in a cool, dry, and well-ventilated area away from incompatible substances. Containers must remain tightly closed to prevent moisture absorption, which could affect the stability of the boronic acid group. We offer flexible packaging options, including standard 25kg drums, and can customize packaging solutions based on specific logistical requirements or bulk order volumes.