Intermediates

2-Cyano-3,5-difluoropyridine

  • CAS No.298709-29-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Cyano-3,5-difluoropyridine (CAS 298709-29-2) designed for advanced pharmaceutical synthesis. Reliable supply with ≥98.0% purity for global research and production needs.

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Product Technical Details

Product Overview

2-Cyano-3,5-difluoropyridine represents a critical building block in modern medicinal chemistry and organic synthesis. As a fluorinated heterocyclic compound, this intermediate offers unique reactivity profiles that are essential for the development of novel pharmaceutical agents. Our facility specializes in the production of high-quality chemical intermediates, ensuring that every batch meets rigorous international standards for purity and consistency.

The presence of fluorine atoms at the 3 and 5 positions of the pyridine ring significantly enhances the metabolic stability and lipophilicity of downstream drug candidates. This makes 2-Cyano-3,5-difluoropyridine an invaluable asset for researchers focused on optimizing lead compounds during the drug discovery pipeline. We understand the demanding requirements of the pharmaceutical industry and provide material that supports efficient synthesis routes.

Technical Specifications

ParameterValue
Chemical Name2-Cyano-3,5-difluoropyridine
CAS Number298709-29-2
Molecular FormulaC6H2F2N2
Molecular Weight140.09 g/mol
Purity≥98.0%
AppearancePowder
Melting Point32-34°C
Boiling Point187.8±35.0°C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point67.4±25.9°C

Industrial Applications

This chemical intermediate is primarily utilized in the synthesis of complex pharmaceutical molecules. The cyano group provides a versatile handle for further functionalization, allowing chemists to introduce amides, amines, or tetrazoles through standard transformations. The difluoro substitution pattern is particularly sought after for creating kinase inhibitors and other targeted therapies where specific electronic properties are required.

  • Used as a key starting material in medicinal chemistry campaigns.
  • Employed in the synthesis of agrochemical intermediates requiring fluorinated pyridine scaffolds.
  • Utilized in research and development for creating new organic materials.
  • Serves as a reference standard for analytical method development.

Quality Assurance and Storage

Quality is the cornerstone of our manufacturing process. Each production lot of 2-Cyano-3,5-difluoropyridine undergoes comprehensive analysis using advanced techniques such as HPLC, GC-MS, and NMR spectroscopy. We provide a Certificate of Analysis (COA) with every shipment to verify compliance with specified parameters. Our quality management system ensures traceability and consistency across all batches.

Proper storage is essential to maintain the integrity of this chemical. We recommend storing the product in a tightly closed container within a cool, dry environment. Protection from moisture and direct sunlight is advised to prevent degradation. Our standard packaging consists of 25 kg drums, designed to ensure safety during transit and handling. For specific packaging requirements or bulk orders, our logistics team is available to customize solutions that meet your operational needs.