2-Cyano-5-Fluorobenzyl Bromide
- CAS No.421552-12-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Cyano-5-Fluorobenzyl Bromide is a critical pharmaceutical intermediate used primarily in the synthesis of Trelagliptin. We offer bulk quantities with strict quality control and comprehensive documentation.
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Product Overview
2-Cyano-5-Fluorobenzyl Bromide is a specialized organic compound characterized by its unique fluorinated benzyl structure. This chemical serves as a vital building block in the pharmaceutical industry, specifically designed for complex synthesis pathways. The presence of both cyano and fluoro functional groups enhances its reactivity, making it an ideal candidate for nucleophilic substitution reactions required in advanced drug manufacturing. Our facility produces this intermediate under strict Good Manufacturing Practice (GMP) guidelines to ensure consistency and reliability for downstream API production.
The molecular structure, defined by the formula C8H5BrFN, offers specific chemical properties that facilitate efficient coupling processes. With a molecular weight of 214.03, this compound balances stability with reactivity, allowing chemists to integrate it seamlessly into multi-step synthesis routes. We prioritize the production of high-quality batches that meet international standards, supporting pharmaceutical companies in their development of next-generation therapeutic agents.
Technical Specifications
Quality control is paramount in the production of pharmaceutical intermediates. Each batch undergoes rigorous testing using high-performance liquid chromatography (HPLC) and other analytical methods to verify purity and physical characteristics. The following table outlines the key technical parameters for this product:
| Parameter | Specification |
|---|---|
| CAS Number | 421552-12-7 |
| Molecular Formula | C8H5BrFN |
| Molecular Weight | 214.03 g/mol |
| Appearance | White to yellow solid |
| Purity (HPLC) | ≥98.0% |
| Density | 1.591 g/cm3 |
| Boiling Point | 264.468°C |
| Flash Point | 113.746°C |
| Refractive Index | 1.564 |
Industrial Applications
The primary application of 2-Cyano-5-Fluorobenzyl Bromide is in the synthesis of Trelagliptin, a prominent DPP-4 inhibitor used for the management of type 2 diabetes. As a key precursor, this intermediate enables the construction of the core heterocyclic structures found in modern antidiabetic medications. Its high purity ensures that the final API meets stringent regulatory requirements for safety and efficacy.
Beyond diabetes treatment, fluorinated benzyl bromides are increasingly valuable in medicinal chemistry for developing various neurological and cardiovascular therapeutics. The fluorine atom often improves metabolic stability and bioavailability of the final drug product. Our manufacturing process is optimized to support large-scale production needs, ensuring a stable supply chain for global pharmaceutical partners.
Quality Assurance and Logistics
We understand the critical nature of supply chain integrity in the pharmaceutical sector. All products are packaged in 25 kg drums, with customization available to meet specific client requirements. Storage recommendations include keeping the material in a cool, ventilated place away from direct sunlight and moisture to maintain chemical stability. Each shipment is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results.
Compliance with intellectual property rights is strictly observed. Please note that products covered by valid patents will not be offered to countries where such patents are in force. Our team is dedicated to providing transparent communication, competitive bulk pricing, and reliable global shipping solutions to support your research and manufacturing objectives.
