2-Cyanopyrazine
- CAS No.19847-12-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Cyanopyrazine (CAS 19847-12-2), a key heterocyclic intermediate for pharmaceutical and agrochemical synthesis.
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Product Overview
2-Cyanopyrazine (CAS 19847-12-2) is a versatile nitrogen-containing heterocyclic compound widely employed as a critical building block in the synthesis of active pharmaceutical ingredients (APIs) and specialty agrochemicals. With its reactive nitrile group adjacent to the electron-deficient pyrazine ring, it serves as an excellent electrophilic synthon for nucleophilic addition, cycloaddition, and cross-coupling reactions in advanced organic synthesis.
Specifications
| Molecular Formula | C₅H₃N₃ |
|---|---|
| Molecular Weight | 105.10 g/mol |
| Appearance | Slightly green transparent liquid |
| Melting Point | 18–20 °C (tested: 22 °C) |
| Boiling Point | 87 °C at 6 mmHg |
| Density | 1.174 g/cm³ |
| Refractive Index | 1.534 |
| Assay (GC) | ≥99.0% (tested: 99.57%) |
| Moisture (KF) | ≤0.2% (tested: 0.08%) |
Industrial Applications
As a high-value chemical intermediate, 2-Cyanopyrazine is primarily utilized in the pharmaceutical industry for the construction of complex molecular architectures, including kinase inhibitors, antimicrobial agents, and central nervous system modulators. Its structural motif also finds application in the development of novel crop protection agents and functional materials. Due to its reactivity and stability under controlled conditions, it is compatible with large-scale GMP manufacturing processes.
- Enables efficient synthesis of fused pyrazine derivatives via nitrile transformation
- Suitable for multi-step API campaigns requiring stringent impurity control
- Supplied with full analytical documentation including COA and spectral data
