2-(Dimethylamino)thioacetamide hydrochloride
- CAS No.27366-72-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2-(Dimethylamino)thioacetamide hydrochloride serving as a key pharmaceutical intermediate for Nizatidine synthesis with ≥98% assay.
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Product Overview
2-(Dimethylamino)thioacetamide hydrochloride is a specialized organic compound widely recognized in the pharmaceutical industry for its critical role in synthetic chemistry. This high-value intermediate features a thioacetamide backbone substituted with a dimethylamino group, stabilized as a hydrochloride salt to enhance handling and solubility during reaction processes. Our manufacturing facility ensures that every batch meets rigorous international standards for purity and consistency, making it an ideal choice for complex drug synthesis pathways.
As a dedicated supplier of advanced chemical intermediates, we understand the precision required in pharmaceutical production. This compound is primarily utilized in the construction of heterocyclic structures found in various therapeutic agents. The stability of the hydrochloride form allows for safer storage and more predictable reactivity compared to the free base, facilitating smoother scale-up from laboratory research to industrial manufacturing.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 2-(Dimethylamino)thioacetamide hydrochloride |
| CAS Registry Number | 27366-72-9 |
| Molecular Formula | C4H11ClN2S |
| Molecular Weight | 154.66 g/mol |
| Purity Assay | ≥98.0% |
| Appearance | White to beige crystalline powder |
| Density | 1.069 g/cm3 |
| Boiling Point | 176°C at 760 mmHg |
| Flash Point | 60.3°C |
Industrial Applications
The primary application of this chemical lies in the synthesis of pharmaceutical active ingredients, specifically serving as a crucial building block for Nizatidine. Nizatidine is a well-known histamine H2 receptor antagonist used in the treatment of peptic ulcer diseases and gastroesophageal reflux. The high purity of our intermediate ensures that downstream reactions proceed with minimal side products, thereby reducing purification costs and improving overall yield in the final drug substance production.
Beyond its specific use in gastric therapeutics, this thioacetamide derivative demonstrates versatility in organic synthesis laboratories. It is frequently employed in the development of novel sulfur-containing compounds where the introduction of a dimethylamino thioamide moiety is required. Researchers value this material for its reliable performance in nucleophilic substitution reactions and cyclization processes.
Quality Assurance and Storage
Quality control is paramount in our production process. Each lot undergoes comprehensive analysis using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy to confirm identity and purity. A Certificate of Analysis (COA) is provided with every shipment, detailing test results against specified parameters. We maintain strict documentation protocols to ensure full traceability from raw material sourcing to final packaging.
- Packaged in 25kg cardboard drums or customized containers.
- Stored in tightly closed containers in a cool, dry area.
- Protected from moisture and incompatible substances.
- Ventilated storage facilities to ensure safety compliance.
Proper storage conditions are essential to maintain the integrity of the hydrochloride salt. We recommend keeping the material away from strong oxidizing agents and sources of ignition due to its flash point characteristics. Our logistics team ensures secure global shipping, adhering to all relevant transportation regulations for chemical goods. For bulk procurement inquiries or technical support regarding synthesis routes, our expert team is available to assist with customized solutions.
