2-Fluoro-3-iodo-5-methylpyridine
- CAS No.153034-78-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical building block used in organic synthesis for advanced drug discovery projects.
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Product Overview
2-Fluoro-3-iodo-5-methylpyridine represents a highly specialized heterocyclic compound essential for modern medicinal chemistry and organic synthesis. As a fluorinated pyridine derivative, this chemical intermediate offers unique reactivity profiles due to the presence of both fluorine and iodine substituents on the pyridine ring. These halogen atoms facilitate various cross-coupling reactions, making this compound a valuable building block for constructing complex pharmaceutical architectures.
Our manufacturing process ensures exceptional consistency and purity levels suitable for rigorous research and development environments. The strategic placement of the methyl group further enhances the lipophilicity and metabolic stability of downstream molecules synthesized using this precursor. This product is extensively utilized in the discovery of kinase inhibitors, receptor modulators, and other therapeutic agents where precise structural modification is critical.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 2-Fluoro-3-iodo-5-methylpyridine |
| CAS Number | 153034-78-7 |
| Molecular Formula | C6H5FIN |
| Molecular Weight | 237.01 g/mol |
| Appearance | White Crystalline Powder |
| Purity | ≥99.0% |
| Density | 1.182 g/cm3 |
| Boiling Point | 201.7°C at 760mmHg |
| Flash Point | 91.1°C |
| Refractive Index | 1.587 |
Industrial Applications
This compound serves as a versatile intermediate in the synthesis of advanced organic molecules. The iodine atom allows for palladium-catalyzed coupling reactions such as Suzuki, Heck, and Sonogashira couplings, while the fluorine atom can influence the electronic properties and bioavailability of the final drug candidate. Researchers utilize this building block to introduce specific structural motifs required for optimizing pharmacokinetic properties.
Key application areas include:
- Development of novel pharmaceutical active ingredients
- Synthesis of agrochemical compounds
- Material science research involving heterocyclic polymers
- Custom organic synthesis for academic and industrial laboratories
Quality Assurance and Handling
We adhere to strict quality control protocols to ensure every batch meets the specified purity standards. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing test results against established parameters. Proper handling procedures are recommended to maintain product integrity. Store in a tightly closed container in a cool, dry environment away from incompatible materials. Standard laboratory safety practices should be observed during use, including the use of appropriate personal protective equipment.
Our global logistics network ensures timely delivery while maintaining product stability during transit. For large-scale production needs, we offer flexible packaging options and competitive bulk pricing structures to support your manufacturing requirements.
