2-Fluoro-3-iodobenzoic acid
- CAS No.447464-03-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoro-3-iodobenzoic acid (CAS 447464-03-1) designed for advanced organic synthesis and pharmaceutical intermediate applications.
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Product Overview
2-Fluoro-3-iodobenzoic acid is a highly specialized halogenated aromatic compound that serves as a critical building block in modern medicinal chemistry and agrochemical development. This sophisticated intermediate features a unique substitution pattern on the benzoic acid backbone, incorporating both fluorine and iodine atoms at the ortho and meta positions respectively. Such structural configuration provides exceptional reactivity for cross-coupling reactions, making it an indispensable reagent for synthetic chemists aiming to construct complex molecular architectures.
Our manufacturing process ensures that every batch meets rigorous international standards for purity and consistency. The presence of the fluorine atom enhances metabolic stability in potential drug candidates, while the iodine moiety offers a versatile handle for further functionalization through palladium-catalyzed coupling methodologies. This dual functionality makes the compound particularly valuable in the discovery and optimization of new pharmaceutical agents.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2-Fluoro-3-iodobenzoic acid |
| CAS Number | 447464-03-1 |
| Molecular Formula | C7H4FIO2 |
| Molecular Weight | 266.01 g/mol |
| Purity | ≥99.0% |
| Density | 2.074 g/cm3 |
| Boiling Point | 331.02 °C |
| Flash Point | 153.99 °C |
| Refractive Index | 1.638 |
Industrial Applications
This compound is primarily utilized as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its specific halogenation pattern allows for selective transformations that are difficult to achieve with non-halogenated analogs. Researchers frequently employ this material in the development of kinase inhibitors, anti-inflammatory agents, and other therapeutic classes where precise spatial arrangement of functional groups is crucial for biological activity.
- Pharmaceutical intermediate synthesis for novel drug discovery
- Agrochemical formulation development requiring halogenated precursors
- Material science applications involving functionalized aromatic systems
- Custom organic synthesis projects requiring high-purity building blocks
Quality Assurance and Packaging
We maintain a comprehensive quality control system that includes advanced analytical testing such as HPLC, NMR, and GC-MS to verify the identity and purity of each production lot. Every shipment is accompanied by a Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS) to ensure full compliance with regulatory requirements. Our commitment to quality ensures that customers receive materials that perform consistently in their downstream processes.
Standard packaging consists of 25 kg drums lined with protective polyethylene bags to prevent moisture absorption and contamination. We also offer flexible packaging solutions tailored to specific customer requirements, including smaller quantities for research and development purposes. Our logistics team coordinates global shipping to ensure timely delivery while maintaining product integrity during transit.
Storage and Handling
To maintain optimal stability, 2-Fluoro-3-iodobenzoic acid should be stored in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. The container must be kept tightly closed when not in use to prevent exposure to atmospheric moisture. Personnel handling this chemical should adhere to standard laboratory safety protocols, including the use of appropriate personal protective equipment such as gloves and safety goggles. Proper storage conditions ensure the long-term viability of the product for future synthesis campaigns.
