Intermediates

2-Fluoro-3-methylphenol

  • CAS No.77772-72-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Fluoro-3-methylphenol (CAS 77772-72-6) designed for advanced organic synthesis. Reliable supply for pharmaceutical and agrochemical intermediate manufacturing.

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Product Technical Details

Product Overview

2-Fluoro-3-methylphenol is a specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. Characterized by the presence of both fluorine and methyl substituents on the phenolic ring, this chemical reagent offers unique reactivity profiles essential for developing complex molecular structures. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for research laboratories and industrial production facilities focused on pharmaceuticals and agrochemicals.

The introduction of fluorine atoms into organic molecules often enhances metabolic stability and bioavailability, which is why this intermediate is highly valued in medicinal chemistry. We maintain strict quality control protocols to guarantee consistency across every batch, supporting our partners in achieving reliable synthesis outcomes.

Key Specifications

Our production facility adheres to international quality standards to deliver materials that meet rigorous technical requirements. The following table outlines the primary physical and chemical properties associated with this product.

ParameterValue
CAS Number77772-72-6
Molecular FormulaC7H7FO
Molecular Weight126.128 g/mol
AppearanceColorless transparent liquid
Assay (Purity)≥98.0%
Density1.2±0.1 g/cm3
Boiling Point174.2±20.0 °C at 760 mmHg
Flash Point67.4±10.5 °C
Refractive Index1.520

Industrial Applications

This fluorinated phenol derivative is primarily utilized as a versatile intermediate in the synthesis of higher-order chemical compounds. Its specific substitution pattern allows for selective functionalization, enabling chemists to construct diverse molecular architectures. Common applications include serving as a precursor in the development of active pharmaceutical ingredients (APIs) and specialized agrochemical formulations.

  • Used in nucleophilic aromatic substitution reactions.
  • Employed in cross-coupling processes such as Suzuki or Buchwald reactions.
  • Acts as a key fragment in the design of kinase inhibitors.
  • Utilized in the production of liquid crystals and advanced materials.

By leveraging the electron-withdrawing nature of the fluorine atom, synthetic chemists can modulate the electronic properties of the final product, optimizing performance characteristics for specific end-use applications.

Quality Assurance and Packaging

We understand that consistency is paramount in chemical manufacturing. Each production lot undergoes comprehensive analysis using advanced techniques such as Gas Chromatography (GC) and High-Performance Liquid Chromatography (HPLC) to verify purity and identity. A Certificate of Analysis (COA) is provided with every shipment to ensure full transparency and compliance with your internal quality standards.

For logistics, the product is securely packaged in 200 kg drums to maintain integrity during transit. Custom packaging solutions are available upon request to accommodate specific supply chain requirements. Proper storage in a cool, ventilated area is recommended to preserve stability. Our global distribution network ensures timely delivery, supported by dedicated technical support teams ready to assist with synthesis route optimization and safety handling guidelines.