Intermediates

2-Fluoro-3-methylpyridine

  • CAS No.2369-18-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Fluoro-3-methylpyridine is a essential fluorinated building block for pharmaceutical synthesis. Available in bulk with strict quality control.

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Product Technical Details

Product Overview

2-Fluoro-3-methylpyridine is a highly valued fluorinated heterocyclic compound widely recognized for its utility in modern organic synthesis and pharmaceutical development. As a key intermediate, this chemical serves as a fundamental building block for constructing more complex molecular structures. The introduction of a fluorine atom at the second position of the pyridine ring significantly alters the electronic properties and metabolic stability of downstream products, making it indispensable in medicinal chemistry.

Our manufacturing process ensures that every batch meets rigorous international standards for purity and consistency. We understand that reliability in the supply chain is critical for research and production timelines. Therefore, we employ advanced distillation and purification techniques to deliver a product that supports high-yield reactions in laboratory and industrial settings.

Physical and Chemical Properties

This compound presents as a clear, colorless liquid under standard conditions, facilitating easy handling and integration into various solvent systems. The physical constants, including density and boiling point, are tightly controlled to ensure reproducibility in synthesis protocols. The presence of the fluorine substituent enhances the lipophilicity of the molecule, which is often a desired trait when designing active pharmaceutical ingredients.

Stability is a key feature of this material. When stored according to recommended guidelines, it maintains its integrity over extended periods. The refractive index and flash point are consistent with high-grade chemical standards, providing chemists with the predictable behavior necessary for scale-up processes.

Quality Specifications

We adhere to strict quality assurance protocols to guarantee that our 2-Fluoro-3-methylpyridine exceeds industry expectations. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) verifying all critical parameters.

ParameterSpecification
AppearanceColorless liquid
Purity≥99.0%
CAS Number2369-18-8
Molecular FormulaC6H6FN
Molecular Weight111.12 g/mol
Density1.098 g/mL at 25 °C
Boiling Point154-155 °C
Flash Point119 °F
Refractive Index1.586

Industrial Applications

The primary application of this fluorinated pyridine derivative lies in the synthesis of advanced pharmaceutical intermediates. It is frequently utilized in the development of therapeutic agents targeting specific neurological and physiological pathways. Researchers value this compound for its reactivity in nucleophilic substitution reactions, allowing for the efficient construction of diverse chemical libraries.

Beyond pharmaceuticals, this material finds use in the agrochemical sector and material science research. Its versatility makes it a preferred choice for chemists looking to introduce fluorine motifs into organic frameworks. Whether for custom synthesis projects or large-scale manufacturing, our product provides a reliable foundation for innovation.

Storage and Handling

To maintain optimal quality, 2-Fluoro-3-methylpyridine should be stored in a tightly closed container within a cool, dry, and well-ventilated area. It is important to protect the material from moisture and direct sunlight. Standard safety precautions for handling organic chemicals should be observed, including the use of appropriate personal protective equipment. We offer flexible packaging options, including 25 kg drums, to suit various logistical requirements and ensure safe global transportation.