Intermediates

2-Fluoro-3-Nitrobenzoic Acid

  • CAS No.317-46-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Fluoro-3-Nitrobenzoic Acid (CAS 317-46-4) designed for advanced organic synthesis and pharmaceutical intermediate applications. Available in bulk quantities with comprehensive COA.

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Product Technical Details

Product Overview

2-Fluoro-3-Nitrobenzoic Acid represents a critical fluorinated building block within the realm of advanced organic synthesis. As a specialized intermediate, this compound is engineered to meet the rigorous demands of modern pharmaceutical and agrochemical research laboratories. The strategic placement of the fluorine atom ortho to the carboxylic acid group, combined with the meta-nitro substitution, creates a unique electronic environment that facilitates diverse nucleophilic aromatic substitution reactions. Our manufacturing process ensures consistent quality, making it an ideal candidate for complex multi-step synthesis pathways.

In the context of medicinal chemistry, fluorinated aromatic compounds are highly valued for their ability to modulate metabolic stability and bioavailability. This specific benzoic acid derivative serves as a versatile precursor for constructing heterocyclic systems and functionalized aromatic cores. Whether utilized in the development of novel therapeutic agents or high-performance materials, the reliability of the raw material is paramount. We adhere to strict production protocols to guarantee batch-to-batch consistency, supporting our partners in achieving their research and development milestones efficiently.

Chemical Properties and Reactivity

The chemical structure of 2-Fluoro-3-Nitrobenzoic Acid imparts distinct physical and chemical properties that are essential for process chemists. The presence of the electron-withdrawing nitro group enhances the reactivity of the fluorine substituent towards nucleophiles, enabling efficient displacement reactions under controlled conditions. Furthermore, the carboxylic acid functionality allows for various derivatization options, including esterification and amide formation. Understanding these properties is crucial for optimizing reaction conditions and maximizing yield in industrial applications.

Safety and handling are integral to our supply chain management. This compound should be managed according to standard laboratory safety practices for fine chemicals. Proper storage conditions maintain the integrity of the product over extended periods, ensuring that the physical appearance and chemical purity remain within specified limits upon delivery to your facility. We understand that impurities can significantly impact downstream reaction yields. Therefore, our purification processes are optimized to minimize trace contaminants.

Industrial Applications

Our clients utilize this intermediate across a broad spectrum of chemical industries. Key application areas include:

  • Pharmaceutical Intermediate Synthesis: Serving as a core structure for developing new drug candidates.
  • Agrochemical Development: Used in the creation of advanced herbicides and pesticides.
  • Material Science: Employed in the synthesis of specialized polymers and functional materials.
  • Custom Organic Synthesis: Available for bespoke research projects requiring high-purity starting materials.

Quality Specifications

We maintain a robust quality assurance system to verify that every shipment meets the agreed-upon standards. Analytical testing is performed using high-performance liquid chromatography (HPLC) to confirm purity levels. Documentation such as Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS) are provided with every shipment to facilitate regulatory compliance and safe handling procedures within your facility. The following table outlines the typical specifications for our commercial grade material:

ParameterValue
CAS Number317-46-4
Molecular FormulaC7H4FNO4
Molecular Weight185.11 g/mol
Purity (HPLC)≥99.0%
AppearanceOff-white to light yellow powder
Density1.52 g/cm3
Boiling Point404.6°C

Packaging and Storage

To ensure product safety during transit, we offer standardized packaging solutions tailored to industrial needs. The standard packing configuration is 25 kg per drum, though we accommodate custom packaging requirements based on volume and client specifications. Storage recommendations include keeping the container tightly closed in a cool, ventilated area away from incompatible substances. By following these guidelines, customers can preserve the quality of the material throughout its shelf life.

Partnering with us provides access to reliable supply chains, comprehensive technical documentation, and responsive customer support. We are committed to facilitating your synthesis projects with premium chemical intermediates that drive innovation.