2-Fluoro-3-nitropyridine
- CAS No.1480-87-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoro-3-nitropyridine (CAS 1480-87-1) designed for advanced pharmaceutical intermediate synthesis and heterocyclic chemistry applications.
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Product Overview
2-Fluoro-3-nitropyridine represents a critical fluorinated heterocyclic compound extensively utilized in modern organic synthesis and medicinal chemistry. As a key building block, this substance facilitates the construction of complex molecular architectures required for advanced therapeutic development. Our manufacturing process ensures exceptional consistency and reliability, making it an ideal choice for research laboratories and industrial production facilities alike.
The unique combination of a fluorine atom and a nitro group on the pyridine ring provides distinct reactivity profiles. This configuration allows chemists to perform selective nucleophilic aromatic substitutions with high precision. The fluorine atom serves as an excellent leaving group, while the nitro group activates the ring towards nucleophilic attack, enabling efficient downstream transformations.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 1480-87-1 |
| Molecular Formula | C5H3FN2O2 |
| Molecular Weight | 142.09 g/mol |
| Appearance | Yellow liquid |
| Purity | >=99.0% |
| Boiling Point | 248.09ºC at 760 mmHg |
| Density | 1.439 g/cm3 |
| Flash Point | 103.84ºC |
| Refractive Index | 1.538 |
Industrial Applications
This fluorinated pyridine derivative finds extensive application in the synthesis of pharmaceutical intermediates. It is particularly valuable in the development of kinase inhibitors and other biologically active molecules where the pyridine scaffold is essential. The compound's stability and reactivity make it suitable for multi-step synthesis routes commonly employed in drug discovery pipelines.
Beyond pharmaceuticals, this material serves as a versatile reagent in agrochemical research and fine chemical production. Its ability to undergo various functional group transformations allows for the creation of diverse chemical libraries. Researchers value this intermediate for its predictable behavior under standard reaction conditions, which streamlines process optimization and scale-up activities.
Quality Assurance and Storage
- Manufactured under strict quality control protocols to ensure batch-to-batch consistency.
- Each shipment includes a comprehensive Certificate of Analysis (COA) verifying purity and physical properties.
- Packaged in secure 25 kg drums to maintain integrity during global transportation.
- Store in a tightly closed container in a cool, dry, and well-ventilated area away from incompatible materials.
- Protect from moisture and direct sunlight to preserve chemical stability over extended periods.
- Handle with appropriate personal protective equipment in accordance with safety data sheet guidelines.
Our commitment to quality ensures that every batch meets rigorous industry standards. We support our clients with technical documentation and responsive customer service to facilitate smooth integration into your production workflows. For large volume requirements or custom packaging options, please contact our sales team for detailed specifications and competitive pricing structures tailored to your specific needs.
