2-Fluoro-4-bromonitrobenzene
- CAS No.321-23-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoro-4-bromonitrobenzene (CAS 321-23-3) designed for advanced organic synthesis and pharmaceutical intermediate manufacturing with reliable quality.
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Product Overview
2-Fluoro-4-bromonitrobenzene is a highly specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. With the CAS registry number 321-23-3, this chemical intermediate is characterized by its unique substitution pattern, featuring both fluorine and bromine atoms on a nitrobenzene ring. This specific arrangement provides versatile reactivity, making it an indispensable raw material for the development of advanced pharmaceuticals, agrochemicals, and functional materials.
Our manufacturing process ensures exceptional purity levels, typically exceeding 98.0% assay. The presence of the fluorine atom enhances metabolic stability in downstream drug candidates, while the bromine moiety offers a robust handle for cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations. We adhere to strict quality control protocols to guarantee consistency across every batch, supporting large-scale industrial production needs.
Technical Specifications
The following table outlines the key physical and chemical properties of our premium grade 2-Fluoro-4-bromonitrobenzene. These parameters are verified through rigorous analytical testing including GC, HPLC, and NMR spectroscopy to ensure compliance with international standards.
| Parameter | Value |
|---|---|
| Chemical Name | 2-Fluoro-4-bromonitrobenzene |
| CAS Number | 321-23-3 |
| Molecular Formula | C6H3BrFNO2 |
| Molecular Weight | 219.996 g/mol |
| Appearance | Yellow crystalline powder |
| Assay | ≥98.0% |
| Melting Point | 83-86 °C |
| Boiling Point | 263.2±20.0 °C |
| Density | 1.8±0.1 g/cm3 |
| Flash Point | 113.0±21.8 °C |
Industrial Applications
This compound is primarily utilized as a key intermediate in the synthesis of complex organic molecules. Its dual halogen functionality allows chemists to perform selective substitutions, enabling the construction of diverse molecular architectures. Common applications include the production of kinase inhibitors and other therapeutic agents where fluorine substitution is required for bioavailability. It also serves as a precursor for herbicides and pesticides that demand high environmental stability. In material science, it is employed in the creation of specialized polymers and liquid crystal materials.
Storage and Handling
To maintain product integrity, 2-Fluoro-4-bromonitrobenzene should be stored in a cool, ventilated area away from direct sunlight and moisture. Containers must be kept tightly closed when not in use. Standard personal protective equipment including gloves and safety goggles should be worn during handling to prevent skin contact or inhalation. We recommend consulting the Safety Data Sheet for comprehensive handling instructions.
Quality Assurance and Supply
As a global manufacturer, we prioritize supply chain reliability. Each shipment is accompanied by a Certificate of Analysis to verify compliance with specified standards. Our packaging options include 25 kg drums, with customization available to meet specific logistical requirements. We are committed to providing competitive bulk pricing and timely delivery to support your research and production schedules.
