2-Fluoro-4-hydroxybenzonitrile
- CAS No.82380-18-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoro-4-hydroxybenzonitrile (CAS 82380-18-5) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and chemical manufacturing.
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Product Overview
2-Fluoro-4-hydroxybenzonitrile represents a critical fluorinated aromatic compound utilized extensively within the fine chemical and pharmaceutical sectors. As a specialized building block, this molecule combines the reactivity of a nitrile group with the metabolic stability imparted by the fluorine substituent. Our manufacturing facility produces this intermediate under strict quality control protocols to ensure consistency across large-scale batches. The presence of the hydroxy group at the para position relative to the nitrile functionality allows for diverse derivatization pathways, making it an invaluable asset for medicinal chemists and process engineers alike.
We understand that reproducibility is paramount in chemical synthesis. Therefore, every batch of 2-Fluoro-4-hydroxybenzonitrile undergoes rigorous analytical testing. This commitment to quality ensures that downstream reactions proceed with predictable yields and minimal impurity profiles. Whether used in the development of novel active pharmaceutical ingredients or advanced agrochemical formulations, our product provides a reliable foundation for complex molecular architectures.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2-Fluoro-4-hydroxybenzonitrile |
| CAS Number | 82380-18-5 |
| Molecular Formula | C7H4FNO |
| Molecular Weight | 137.111 g/mol |
| Appearance | White crystalline powder |
| Assay | ≥98.0% |
| Moisture Content | ≤0.5% |
| Melting Point | 123-126°C |
| Boiling Point | 285.4±25.0°C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
Industrial Applications
This fluorinated intermediate serves as a versatile precursor in multiple high-value industries. In pharmaceutical research, it is frequently employed to introduce fluorine atoms into drug candidates, enhancing bioavailability and metabolic resistance. The nitrile group offers a handle for further transformation into amines, acids, or heterocycles, facilitating the construction of complex therapeutic molecules. Beyond human health, this compound finds utility in the agrochemical sector, where fluorinated structures often confer improved pesticidal activity and environmental stability.
- Key building block for kinase inhibitors and receptor modulators.
- Essential component in the synthesis of liquid crystal materials.
- Used in the development of novel agrochemical active ingredients.
- Supports research into fluorescent probes and imaging agents.
Quality Assurance and Storage
Our commitment to excellence extends beyond production to packaging and logistics. Each drum is sealed to prevent moisture ingress, preserving the integrity of the white crystalline powder during transit. We provide comprehensive documentation, including Certificates of Analysis (COA), to verify compliance with specified parameters. Proper storage is essential to maintain product quality over time. We recommend keeping the material in a cool, ventilated environment away from direct sunlight and incompatible substances. By adhering to these guidelines, customers can ensure optimal performance in their respective synthesis processes. Our global supply chain capabilities allow us to meet demanding timelines, supporting both pilot-scale experiments and full commercial production runs.
