2-Fluoro-4-iodoaniline
- CAS No.29632-74-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoro-4-iodoaniline (CAS 29632-74-4) designed for advanced organic synthesis and pharmaceutical intermediate applications with reliable global supply.
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Product Overview
2-Fluoro-4-iodoaniline is a highly specialized halogenated aromatic amine that serves as a critical building block in modern organic synthesis. Characterized by the presence of both fluorine and iodine substituents on the benzene ring, this compound offers unique reactivity profiles that are essential for the development of complex molecular structures. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for researchers and industrial chemists focused on pharmaceutical and agrochemical innovation.
The strategic placement of the fluoro and iodo groups allows for versatile chemical transformations. The iodine atom facilitates various cross-coupling reactions, such as Suzuki-Miyaura or Heck couplings, while the fluorine atom can significantly influence the metabolic stability and bioavailability of the final active pharmaceutical ingredients. As a trusted global manufacturer, we prioritize consistency and quality in every batch produced.
Key Physical and Chemical Properties
| Property | Specification |
|---|---|
| CAS Number | 29632-74-4 |
| Molecular Formula | C6H5FIN |
| Molecular Weight | 237.014 g/mol |
| Appearance | Light yellow to brown crystalline powder |
| Assay | ≥98.0% |
| Melting Point | 55-57 °C (lit.) |
| Boiling Point | 261.7±25.0 °C at 760 mmHg |
| Density | 2.0±0.1 g/cm3 |
| Flash Point | 112.1±23.2 °C |
| Refractive Index | 1.657 |
Industrial Applications
This fluorinated aniline derivative is predominantly utilized as a key intermediate in the synthesis of advanced medicinal compounds. Its structural features make it particularly valuable in the creation of kinase inhibitors and other targeted therapies where specific halogen substitution patterns are required. Beyond pharmaceuticals, it finds application in the agrochemical sector for the development of novel herbicides and pesticides.
- Pharmaceutical Intermediate: Essential for constructing complex drug molecules requiring halogenated aromatic cores.
- Agrochemical Synthesis: Used in the production of high-performance crop protection agents.
- Material Science: Applicable in the development of specialized organic materials and polymers.
- Cross-Coupling Reactions: Ideal substrate for palladium-catalyzed coupling processes due to the reactive iodo group.
Quality Assurance and Packaging
Quality control is paramount in our production facility. Each batch of 2-Fluoro-4-iodoaniline undergoes rigorous testing using advanced analytical techniques, including HPLC and GC-MS, to verify identity and purity. We provide a comprehensive Certificate of Analysis (COA) with every shipment to ensure compliance with your specific project requirements.
Standard packaging consists of 25 kg drums, which are designed to maintain product integrity during transit. However, we understand that different projects have varying needs, so we offer flexible packaging solutions according to customer requirements. For optimal stability, the product should be stored in a cool, ventilated place, away from direct sunlight and moisture. By choosing our facility, you gain access to a reliable supply chain backed by decades of experience in the chemical industry.
