Intermediates

2-Fluoro-4-(methoxycarbonyl)phenylboronic acid

  • CAS No.603122-84-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Fluoro-4-(methoxycarbonyl)phenylboronic acid (CAS 603122-84-5) designed for advanced pharmaceutical synthesis. Reliable supply with COA.

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Product Technical Details

Product Overview

2-Fluoro-4-(methoxycarbonyl)phenylboronic acid is a specialized organic building block extensively utilized in modern medicinal chemistry and pharmaceutical development. As a key boronic acid derivative, this compound serves as a critical precursor in the synthesis of complex biologically active molecules. Our manufacturing process ensures consistent quality, making it an ideal choice for research laboratories and industrial production facilities focused on advanced organic synthesis.

The presence of both fluoro and methoxycarbonyl functional groups on the phenyl ring provides unique reactivity profiles, enabling chemists to construct diverse molecular architectures. This versatility is particularly valuable in the development of new therapeutic agents where precise structural modification is required to optimize pharmacokinetic properties.

Key Specifications

We adhere to strict quality control standards to guarantee the performance of this intermediate in downstream reactions. Each batch undergoes rigorous analytical testing to confirm identity and purity levels. The following table outlines the typical physical and chemical properties associated with this product.

ParameterSpecification
CAS Number603122-84-5
Molecular FormulaC8H8BFO4
Molecular Weight197.96 g/mol
AppearanceWhite powder
Assay≥98.0%
Water Content≤0.50%
Melting Point173-175°C
Density1.33 g/cm3

Industrial Applications

This boronic acid derivative is primarily employed as a pharmaceutical intermediate. Its primary utility lies in palladium-catalyzed cross-coupling reactions, specifically the Suzuki-Miyaura coupling. This reaction type is fundamental in forming carbon-carbon bonds, allowing for the efficient assembly of biaryl structures commonly found in drug candidates.

  • High compatibility with various catalytic systems.
  • Stable under standard storage conditions.
  • Suitable for scale-up from gram to kilogram quantities.
  • Essential for constructing fluorinated aromatic compounds.

Researchers value this compound for its reliability in forming complex scaffolds required for neurological therapeutics and other advanced organic synthesis projects. The high purity level minimizes side reactions, ensuring higher yields in final product formation.

Storage and Packaging

To maintain optimal stability, 2-Fluoro-4-(methoxycarbonyl)phenylboronic acid should be stored in a cool, dry, and well-ventilated area. Containers must remain tightly closed to prevent moisture absorption, which can affect the quality of boronic acids over time. We offer flexible packaging solutions, typically supplying in 25kg drums, though custom packaging configurations are available upon request to meet specific logistical requirements.

As a non-dangerous good, transportation is straightforward, complying with standard international shipping regulations. Our global supply chain ensures timely delivery to support your production schedules without interruption.