Intermediates

2-Fluoro-4-(trifluoromethyl)benzonitrile

  • CAS No.146070-34-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade 2-Fluoro-4-(trifluoromethyl)benzonitrile designed for advanced organic synthesis and pharmaceutical intermediate applications with verified purity standards.

Request Bulk Pricing

Product Technical Details

Product Overview

2-Fluoro-4-(trifluoromethyl)benzonitrile represents a critical fluorinated aromatic building block extensively utilized in modern medicinal chemistry and agrochemical development. This specialized intermediate features a unique substitution pattern that enhances metabolic stability and lipophilicity in downstream molecular structures. Our manufacturing process ensures consistent quality suitable for complex synthetic routes requiring high precision and reliability.

As a key component in the synthesis of kinase inhibitors and other therapeutic agents, this compound offers superior reactivity profiles. The presence of both fluoro and trifluoromethyl groups provides distinct electronic properties that facilitate nucleophilic aromatic substitution reactions. We maintain strict control over production parameters to deliver material that meets rigorous international standards for pharmaceutical intermediates.

Key Specifications

ParameterSpecification
Chemical Name2-Fluoro-4-(trifluoromethyl)benzonitrile
CAS Number146070-34-0
Molecular FormulaC8H3F4N
Molecular Weight189.11 g/mol
Purity≥99.0%
AppearanceWhite to light yellow crystal powder
Melting Point103-105oC
Boiling Point178-180oC
Density1.358 g/cm3

Industrial Applications

This fluorinated benzonitrile derivative serves as a versatile precursor in the production of high-value active pharmaceutical ingredients. Its structural characteristics make it particularly valuable for developing compounds targeting central nervous system disorders and oncology indications. Researchers utilize this intermediate to introduce specific fluorine motifs that improve bioavailability and binding affinity in final drug candidates.

Beyond pharmaceuticals, the compound finds application in agrochemical synthesis where fluorine substitution enhances pesticidal activity and environmental stability. Our supply chain supports both research-scale quantities and large-volume commercial production requirements. We provide comprehensive technical documentation to assist process chemists in optimizing reaction conditions and scaling operations efficiently.

Quality Assurance and Storage

Every batch undergoes rigorous analytical testing including HPLC, GC-MS, and NMR spectroscopy to confirm identity and purity levels. We issue a Certificate of Analysis with each shipment to ensure full traceability and compliance with quality management systems. Proper storage involves keeping the material in a cool, ventilated environment away from moisture and incompatible substances to maintain stability over extended periods.

Packaging options include standard 25 kg drums with customizable solutions available upon request to meet specific logistical needs. Our commitment to safety and quality makes us a preferred partner for global organizations seeking reliable sources of specialized chemical intermediates. Contact our technical team for detailed safety data sheets and customization inquiries regarding this essential fluorinated building block.