2-Fluoro-5-formylbenzoic acid
- CAS No.550363-85-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoro-5-formylbenzoic acid (CAS 550363-85-4) designed for pharmaceutical synthesis. Reliable supply for Olaparib production with strict quality control.
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Product Overview
2-Fluoro-5-formylbenzoic acid represents a critical building block in modern medicinal chemistry, specifically within the realm of oncology therapeutics. As a fluorinated aromatic compound, this molecule offers unique reactivity profiles essential for constructing complex pharmaceutical architectures. Our facility specializes in the large-scale production of this high-value intermediate, ensuring consistent quality for downstream synthesis processes. The presence of both fluoro and formyl functional groups on the benzoic acid backbone allows for versatile coupling reactions, making it indispensable for researchers and manufacturers focused on advanced drug development.
We understand the stringent requirements of the pharmaceutical supply chain. Therefore, every batch undergoes rigorous analytical testing to confirm identity and purity. Our commitment to excellence ensures that clients receive materials that meet or exceed international standards for pharmaceutical intermediates. This product is particularly valued for its role in the synthesis of PARP inhibitors, contributing to the global effort in developing effective cancer treatments.
Technical Specifications
Quality control is paramount in our manufacturing process. We utilize state-of-the-art instrumentation including HPLC, NMR, and Mass Spectrometry to validate every parameter. The following table outlines the standard specifications for our commercial grade material. Custom specifications may be available upon request for specific project requirements.
| Parameter | Specification |
|---|---|
| Chemical Name | 2-Fluoro-5-formylbenzoic acid |
| CAS Number | 550363-85-4 |
| Molecular Formula | C8H5FO3 |
| Molecular Weight | 168.12 g/mol |
| Appearance | Pale brown solid |
| Purity (HPLC) | ≥98.0% |
| Total Impurities | ≤0.5% |
| Melting Point | 174.5-178.5°C |
| Boiling Point | 330.9°C at 760 mmHg |
| Density | 1.427 g/cm3 |
Industrial Applications
This compound serves primarily as a key intermediate in the manufacturing of sophisticated pharmaceutical agents. Its most notable application is in the synthesis pathway of Olaparib, a prominent medication used in the treatment of various cancers. The chemical stability and reactivity of the formyl group facilitate crucial condensation and reduction steps during multi-step synthesis. Beyond oncology, fluorinated benzoic acids are increasingly utilized in agrochemical research and material science due to their enhanced metabolic stability and lipophilicity.
- Essential building block for PARP inhibitor synthesis
- Used in developing novel kinase inhibitors
- Applicable in radiolabeling studies for drug metabolism
- Supports custom synthesis projects for biotech firms
Storage and Handling
Proper storage conditions are vital to maintain the integrity of 2-Fluoro-5-formylbenzoic acid. The material should be kept in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Containers must remain tightly closed to prevent moisture absorption, which could affect purity over time. We recommend using standard personal protective equipment during handling, including gloves and safety goggles. Our packaging options include 25kg cardboard drums, with flexible logistics solutions available to meet global shipping requirements. Safety data sheets and certificates of analysis are provided with every shipment to ensure full regulatory compliance.
