2-Fluoro-5-iodopyridine
- CAS No.171197-80-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoro-5-iodopyridine (CAS 171197-80-1) designed for pharmaceutical synthesis. Reliable supply with strict quality control.
Request Bulk PricingProduct Technical Details
Product Overview
2-Fluoro-5-iodopyridine is a highly specialized heterocyclic building block extensively utilized in the field of medicinal chemistry and advanced organic synthesis. As a halogenated pyridine derivative, this compound serves as a critical intermediate for the construction of complex pharmaceutical architectures and agrochemical structures. The presence of both fluorine and iodine substituents on the pyridine ring provides unique reactivity profiles, enabling diverse transformation pathways essential for modern drug discovery programs and material science applications.
Our manufacturing process ensures exceptional consistency and reliability for research and production scales. Each batch undergoes rigorous analytical testing to confirm identity and purity levels before release. This compound is particularly valued for its stability under standard storage conditions while remaining reactive enough for catalytic cross-coupling reactions. We are committed to supplying research institutions and pharmaceutical companies with materials that meet the highest industry standards for safety and performance.
Key Chemical Properties
The physical and chemical characteristics of 2-Fluoro-5-iodopyridine make it suitable for a wide range of synthetic applications. The compound typically presents as a cream-colored crystalline solid. Its specific density and melting point range facilitate easy handling and processing in laboratory and pilot plant settings. The boiling point indicates thermal stability suitable for various reaction conditions requiring elevated temperatures.
| Parameter | Value |
|---|---|
| CAS Number | 171197-80-1 |
| Molecular Formula | C5H3FIN |
| Molecular Weight | 222.99 g/mol |
| Appearance | Cream Crystal |
| Purity | ≥98.0% |
| Density | 2.046 g/cm3 |
| Melting Point | 33-37 °C |
| Boiling Point | 223.8 °C |
| Flash Point | 204 °F |
| Refractive Index | 1.599 |
Industrial Applications
This fluorinated iodopyridine derivative is primarily employed as a key starting material in the synthesis of active pharmaceutical ingredients. The iodine atom serves as an excellent leaving group for palladium-catalyzed coupling reactions, such as Suzuki-Miyaura or Sonogashira couplings. Meanwhile, the fluorine atom can enhance the metabolic stability and bioavailability of the final drug molecule. Common applications include the development of kinase inhibitors, receptor modulators, and novel ligands for catalytic systems.
- Development of kinase inhibitors and receptor modulators.
- Synthesis of agrochemical intermediates requiring heterocyclic cores.
- Construction of novel ligands for catalytic systems.
- Use in structure-activity relationship studies.
- Production of advanced organic materials.
Quality Assurance and Storage
We maintain strict quality control protocols throughout the production lifecycle to ensure product integrity. Certificate of Analysis documents are provided with every shipment to verify specifications against internal standards. To maintain optimal quality, the product should be stored in a tightly closed container within a cool, dry environment away from direct sunlight. Proper handling procedures should be followed to ensure safety and prevent degradation during transport. Our global logistics network ensures timely delivery while maintaining product integrity during transit to any destination.
