2-Fluoro-5-methyl-3-nitropyridine
- CAS No.19346-44-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoro-5-methyl-3-nitropyridine (CAS 19346-44-2) designed for advanced pharmaceutical synthesis. Reliable supply with strict quality control.
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Product Overview
2-Fluoro-5-methyl-3-nitropyridine is a highly specialized fluorinated heterocyclic compound designed for advanced organic synthesis and medicinal chemistry applications. As a critical building block, this nitropyridine derivative features a strategic substitution pattern that enhances its reactivity in nucleophilic aromatic substitution reactions. The presence of the fluorine atom at the second position significantly influences the electronic properties of the pyridine ring, making it an invaluable precursor for developing novel pharmaceutical agents and agrochemical solutions.
Our manufacturing process ensures exceptional consistency and reliability for both research and industrial scale-up. This compound serves as a versatile intermediate in the construction of complex molecular architectures, particularly where metabolic stability and bioavailability are paramount concerns in modern drug design. The nitro group provides a convenient chemical handle for further functionalization through reduction or cross-coupling methodologies, allowing chemists to diversify their synthetic routes efficiently.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 19346-44-2 |
| Molecular Formula | C6H5FN2O2 |
| Molecular Weight | 156.12 g/mol |
| Appearance | White Crystalline Powder |
| Purity | ≥99.0% |
| Boiling Point | 276.2°C at 760 mmHg |
| Density | 1.357 g/cm3 |
| Flash Point | 120.8°C |
Industrial Applications
This fluorinated pyridine derivative is extensively utilized in the pharmaceutical industry as a key intermediate for synthesizing kinase inhibitors and receptor modulators. The specific arrangement of the methyl and nitro groups allows for selective transformations, enabling chemists to introduce diverse functional groups with high precision. Beyond human therapeutics, this chemical finds application in the development of advanced crop protection agents and specialty materials where heterocyclic stability is required.
- Ideal for nucleophilic substitution reactions due to activated fluorine.
- Used in the synthesis of heterocyclic pharmaceutical APIs.
- Supports research in metabolic stability enhancement.
- Compatible with various cross-coupling catalytic systems.
- Suitable for agrochemical intermediate production.
Quality Assurance and Safety
We adhere to strict quality management systems to guarantee the integrity of every batch produced. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) verifying purity, identity, and physical constants. Our facility maintains rigorous environmental controls to prevent contamination and ensure product stability during production and packaging. Safety data sheets are provided to ensure compliant handling across global jurisdictions.
For safe handling, store this material in a tightly closed container within a cool, dry, and well-ventilated area. Avoid exposure to incompatible substances such as strong oxidizing agents or moisture. Proper personal protective equipment, including gloves and safety goggles, should be worn during handling to minimize exposure risks. In case of spillage, follow standard chemical hygiene protocols for containment and disposal according to local regulations.
Why Partner With Us
As a global manufacturer, we offer competitive bulk pricing and reliable logistics solutions tailored to your specific supply chain needs. Our technical support team is available to assist with customization requests and provide detailed documentation for regulatory compliance. We are committed to delivering high-performance chemical intermediates that accelerate your research and development timelines while maintaining the highest standards of safety and quality.
