Intermediates

2-Fluoro-5-methylbenzaldehyde

  • CAS No.93249-44-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Fluoro-5-methylbenzaldehyde (CAS 93249-44-6) is a vital fluorinated building block for pharmaceutical and agrochemical synthesis, available in bulk quantities.

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Product Technical Details

Product Overview

2-Fluoro-5-methylbenzaldehyde is a specialized fluorinated aromatic aldehyde that serves as a fundamental building block in modern organic synthesis. As a key intermediate, this compound leverages the unique electronic properties of the fluorine atom to enhance the metabolic stability and bioavailability of downstream pharmaceutical candidates. Our manufacturing process ensures consistent quality, making it an ideal choice for research and industrial scale production.

The presence of the methyl group at the five-position and the fluorine substituent at the two-position creates a specific steric and electronic environment. This configuration is highly valued in medicinal chemistry for developing kinase inhibitors and other targeted therapies. We provide this material with strict adherence to international quality standards, supporting global supply chains with reliability and precision.

Chemical Properties And Reactivity

The chemical structure of this fluorinated benzaldehyde offers versatile reactivity profiles suitable for complex molecular construction. The aldehyde functionality allows for a wide range of chemical transformations, including reductive amination, Grignard additions, and condensation reactions. These pathways are essential for constructing diverse molecular scaffolds required in drug discovery pipelines and advanced material science applications.

Key Specifications

ParameterValue
Chemical Name2-Fluoro-5-methylbenzaldehyde
CAS Number93249-44-6
Molecular FormulaC8H7FO
Molecular Weight138.14 g/mol
Purity≥99.0%
AppearancePale Yellow Liquid
Boiling Point89°C
Density1.129 g/cm³
Refractive Index1.516

Industrial Applications

This fluorinated benzaldehyde derivative is extensively utilized in the synthesis of complex pharmaceutical agents and agrochemical products. The specific substitution pattern enables chemists to introduce fluorine atoms into lead compounds, often improving binding affinity and pharmacokinetic properties. Our clients rely on this intermediate for creating next-generation therapeutic solutions.

  • Pharmaceutical Intermediate: Used in the preparation of novel therapeutic compounds.
  • Agrochemical Synthesis: Serves as a precursor for advanced crop protection agents.
  • Material Science: Applicable in the development of specialized organic materials.
  • Custom Synthesis: Available for tailored research and development projects.

Quality Assurance And Handling

Quality is paramount in our production facility. Each batch of 2-Fluoro-5-methylbenzaldehyde undergoes rigorous analytical testing using HPLC and GC-MS to verify purity and identity. We provide a comprehensive Certificate of Analysis (COA) with every shipment to ensure transparency and compliance with your internal quality protocols.

For safe handling, store this material in a cool, well-ventilated area away from incompatible substances such as strong oxidizing agents. Containers should remain tightly closed when not in use to prevent moisture absorption or contamination. Our packaging options include standard drums or custom configurations based on specific logistical requirements. Partner with us for a secure and efficient supply of high-performance chemical intermediates.