Intermediates

2-Fluoro-5-methylbenzoic acid

  • CAS No.321-12-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Fluoro-5-methylbenzoic acid (CAS 321-12-0) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and agrochemical intermediates.

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Product Technical Details

Product Overview

2-Fluoro-5-methylbenzoic acid is a specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. As a key intermediate, this chemical facilitates the introduction of fluorine atoms into complex molecular structures, enhancing the metabolic stability and bioavailability of final products. Our manufacturing process ensures consistent quality, making it an ideal choice for research and industrial-scale applications.

The presence of the fluorine substituent at the ortho position relative to the carboxylic acid group imparts unique electronic and steric properties to the molecule. These characteristics are highly valued in medicinal chemistry, where fine-tuning molecular interactions is essential for drug discovery. We adhere to strict production standards to guarantee that every batch meets the rigorous demands of downstream synthesis.

Technical Specifications

Parameter Value
CAS Number 321-12-0
Molecular Formula C8H7FO2
Molecular Weight 154.14 g/mol
Purity (GC) ≥99.0%
Moisture Content ≤0.5%
Appearance White powder

Physical and Chemical Properties

This compound exhibits stable physical properties suitable for various reaction conditions. With a melting point ranging between 160 and 162 degrees Celsius, it demonstrates high thermal stability. The boiling point is approximately 259.2 degrees Celsius, allowing for distillation processes under reduced pressure if necessary. The density of 1.258 g/cm³ reflects its compact molecular structure, while the refractive index of 1.532 indicates its optical characteristics.

The flash point of 110.6 degrees Celsius suggests standard handling precautions typical for organic acids. Proper storage in a cool, ventilated environment maintains its integrity over extended periods. Our quality control team performs comprehensive testing on each production lot to verify these parameters against international standards.

Industrial Applications

  • Pharmaceutical Synthesis: Used as a precursor for developing non-steroidal anti-inflammatory drugs and other therapeutic agents.
  • Agrochemical Production: Serves as a foundational component in the creation of advanced herbicides and pesticides.
  • Liquid Crystal Materials: Utilized in the formulation of specialized materials for display technologies due to its fluorinated structure.
  • Organic Catalysis: Acts as a ligand or additive in specific catalytic processes requiring fluorinated aromatics.

Quality Assurance and Packaging

We prioritize product safety and consistency. Each drum is sealed to prevent moisture absorption and contamination. Standard packaging includes 25 kg drums, though we offer flexible customization to meet specific logistical requirements. Comprehensive documentation, including Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS), accompanies every shipment.

Our global supply chain ensures timely delivery while maintaining compliance with international chemical transport regulations. By choosing our 2-Fluoro-5-methylbenzoic acid, partners gain access to a reliable source of high-performance chemical intermediates backed by decades of industry expertise.